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EC number: 201-224-3
CAS number: 79-77-6
Irritation:- skin: not irritating (OECD 404)- eye: not irritating (OECD 405)
Irritation to skin was analyzed in a study which was performed according
to OECD Guideline 404 (BASF AG, 1992). 0.1 ml of pure substance was
applied to clipped skin of 3 white rabbits for 4 h under semiocclusive
condition. The resulting scores for erythema and edema were 0 at all
observation times. Also, no irritant effects to eye could be detected in
a study with 3 rabbits performed according to OECD Guideline 405 (BASF
AG; 1992). Slight corneal opacity and iritis was observed after 24 hours
of application and conjunctival irritation after 1, 24 and 48 hours, but
all signs of irritation (including corneal opacity) were completely
reversible within 72 hours of observation.
Due to results obtained in studies performed according to OECD
Guidelines 404 and 405, no classification for skin and eye irritation is
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