4-tert-butylpyrocatechol

Boiling point

Link to relevant study record(s)

Reference

Endpoint:

boiling point

Type of information:

experimental study

Adequacy of study:

key study

Study period:

report date: 2010-01-06

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

comparable to guideline study

Qualifier:

according to guideline

Guideline:

OECD Guideline 103 (Boiling point/boiling range)

Deviations:

no

Qualifier:

according to guideline

Guideline:

EU Method A.2 (Boiling Temperature)

Deviations:

no

GLP compliance:

no

Type of method:

differential scanning calorimetry

Key result

Boiling pt.:

290.5 °C

Atm. press.:

1 013 hPa

Atmospheric pressure during the assay has not been measured; the boiling temperature was given without any correction.

Result of the boiling point:

	Test item			Reference item
	Assay 1	Assay 2	Mean(+/- Standard deviation)	Measure	range
Weight (mg)	5.39	5.45	-	5.09	-
Boiling point (°C)	289.8	291.2	290.5 +/- 1.0	249.7	249.0 - 250.5

According to the results of the reference item, the test has to be considered as valid.

Conclusions:

The boiling point of 4-TBC is 290.5°C +/- 0.1°C.

Executive summary:

In a study (Processium, 2010), the boiling point of 4-tert-butylpyrocatechol was assessed using the differential scanning calorimetry, according to the regulation (EC) n°440/2008, A.2, and to the OECD Guideline n°103.

 

A test item amount of 5 mg was heated up from 30 to 300°C with a rate of 10°C/min. During the experiment, two samples were measured. The quantities of heat absorbed or released were measured by Differential Scanning Calorimetry and recorded. A reference sample (around 5 mg) of benzoic acid was measured in order to evaluate the experimental procedure.

The results of the boiling point of 4 -TBC were: 289.8°C and 291.2°C and of the reference item: 249.7°C.

According to the results of the reference item, the test has to be considered as valid.

In conclusion, the boiling point of 4 -tert-butylpyrocatechol is 290.5°C +/- 1.0°C.

This study is classified as acceptable and satisfies the guideline requirements for a boiling point study.

Description of key information

Boiling point: 290.5°C +/- 0.1°C

Key value for chemical safety assessment

Boiling point at 101 325 Pa:

290.5 °C

Additional information

One experimental study (Processium, 2010) with reliability 1 according to Klimisch was available and was selected as key study. Boiling point was determined according to the regulation (EC) n°440/2008, A.2.

Data coming from peer-review handbooks were available. As the values are in the same range, they are used in a supporting approach.