Registration Dossier
Registration Dossier
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EC number: 230-392-0 | CAS number: 7087-68-5
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
No toxicity has been observed during this limit test (mean measured concentration of 69.7 mg/L of EDIPA).
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Dose descriptor:
- LC50
- Effect concentration:
- >= 69.7 mg/L
Additional information
The acute toxicity of ethyldiisopropylamine (EDIPA) to zebra fish was assessed by conducting a limit test at a nominal concentration of 70 mg/L according to OECD 203 test guideline and GLP requirements. The test was conducted under continuous flow conditions. Analysis of test samples indicated that concentrations of EDIPA were maintained at 82 - 121% of nominal over the test period and thus the results were based on mean measured concentrations.
No mortality or other adverse effects were noted throughout the test period and thus the LC50_96h of EDIPA to zebrafish was concluded to be greater than 69.7 mg/L based on geometric mean measured concentrations, under the conditions of the test. The validity criteria were fulfilled.
During the pre equilibration phase, it was found that the addition of EDIPA to reconstituted freshwater increases the pH of the solution to 10.25. As indicated in the OECD 203 guideline, the pH was then adjusted. In order to control the increase in pH, hydrochloric acid was added in order to obtain a pH similar to the control tank.
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