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Toxicological information

Sensitisation data (human)

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Administrative data

Endpoint:
sensitisation data (humans)
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: study data do not give sufficient experimental details

Data source

Reference
Reference Type:
publication
Title:
Alergens in rubber products
Author:
Kanto, H.; et al.
Year:
1999
Bibliographic source:
Toho Igakkai Zasshi, 46(3), 240-250

Materials and methods

Type of sensitisation studied:
skin
Study type:
other: patch-test with dermatitis cases
Principles of method if other than guideline:
other: patch-test
GLP compliance:
not specified

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
no data

Method

Type of population:
not specified
Controls:
no data
Route of administration:
dermal

Results and discussion

Results of examinations:
0/16 and 0/91 positive skin reactions in contact dermatitis patients

Any other information on results incl. tables

Patch-test Reading:

negative

0/16

0/91

Applicant's summary and conclusion

Executive summary:

The test substance 6,6'-di-tert-butyl-2,2'-methylenedi-p-cresol was negative in the patch-test (Kanto 1999).