Registration Dossier

Ecotoxicological information

Long-term toxicity to fish

Currently viewing:

Administrative data

Link to relevant study record(s)

Description of key information

A chronic EC10 > 0.28 mg/L (Upper Threshold Concentration) for Pimephales promelas (OECD 210, flow-through) exposed to Alcohols, C7-9-iso, C8-rich.

Key value for chemical safety assessment

EC10, LC10 or NOEC for freshwater fish:
0.28 mg/L

Additional information

A preliminary exposure assessment using information from long-term test results with daphnids and algae indicated a need to investigate further the effects on aquatic organisms (RCRs to the water compartments were not well below 1 for all the supported uses; i.e., formulation, industrial intermediates and coatings).

A limit test, at the upper threshold concentration (UTC: defined as the lowest of two effect concentrations obtained for algae and daphnids; 0.28 mg/L for the registered substance) was performed and no adverse effects were observed (based on hatch, survival, weight and length). As such, the chronic fish toxicity result is reported as greater than the UTC value.

Experimental long-term toxicity data for the registered substance are adequate for the purpose of classification and labelling and/or risk assessment. Supporting information is provided by acute and chronic aquatic toxicity values calculated using the neutral organics structure-activity relationship in the ECOSAR computer program (Nabholz and Mayo-Bean, 2009) of EPISuite; the results of which are consistent with the measured test data. Validity and applicability of the QSAR are described in a document attached as background material to the QSAR endpoint study record.