Registration Dossier

Environmental fate & pathways

Endpoint summary

Administrative data

Description of key information

Additional information

Bioaccumulation data is used as read across for Alcohols, C7 -9 -iso, C8 -rich.

Both an aqueous exposure bioconcentration test and a dietary exposure bioaccumulation test with Alcohols, C9 -11 -iso-, C10-rich (Isodecanol) were conducted with the rainbow trout, Oncorhynchus mykiss. In the aqueous exposure, the trout reached steady-state within a 16 -day exposure period. The calculated mean lipid normalized steady state BCF was 21.4 L/kg wet fish weight. The calculated dietary, lipid-corrected BMF values were 0.006 to 0.016 (at 500 and 2500 ppm treatment levels), with growth corrected whole body half-lives ranging from 0.55 to 0.21 days.

The registered substance (Isooctanol) and the tested substance (Isodecanol) are part of a closely related group of products with structural similarity, made by the same manufacturing process. (Further detail is provided in the assessment report for read-across.) Their structural and physicochemical properties follow an expected trend with C-chain length. The tested substance is more hydrophobic and has a higher log Kow than the target substance. As BCF is positively correlated with hydrophobicity, these values can be used as a worst-case estimate for Alcohols, C7-9-iso, C8-rich. Both the aqueous and dietary bioaccumulation studies indicate that this substance exhibits a low potential to bioaccumulate.