Registration Dossier
Registration Dossier
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EC number: 200-618-2 | CAS number: 65-85-0
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
Four acute toxicity studies with fish are available. In the key studies with Lepomis macrochirus (Schneider, 1979) and rainbow trout (Schneider, 1979) the LC50 (96 h) values were 44.6 mg/L and 47.3 mg/L respectively, based on nominal concentrations. Two other studies in rainbow trout (Jonas 1998) and the bluegill (Buzzell 1968) showed higher LC50 values. AS these studies are not available for review, in a worst case assumption the LC50 is set at 44.6 mg/L.
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 44.6 mg/L
Additional information
Four acute toxicity studies with fish are available. The key study ( Schneider, 1979) was a static 96 hour study according to
EPA-660/3-75-001with Lepomis macrochirus, where the LC50 was 44.6 mg/L. No analytics were included. The key study (Schneider, 1979) was according to EPA-660/3 -75 -001 with Salmo gairdneri, where the LC50 (96 h) was 47.3 mg/L. The results were confirmed in the supporting study (Jonas, 1998) with Oncorhynchus mykiss, where the LC50 (96 h) was >120 mg/L. The results were confirmed in the supporting study (Buzzell, 1968) with Lepomis macrochirus, where the LC0 (96 h) was shown up to a concentration of 180 mg/L.
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