Registration Dossier

Toxicological information

Carcinogenicity

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Administrative data

Endpoint:
carcinogenicity: inhalation
Type of information:
experimental study
Adequacy of study:
key study

Data source

Reference
Reference Type:
publication
Title:
Unnamed
Year:
2007
Report Date:
2007

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
OECD Guideline 451 (Carcinogenicity Studies)
Deviations:
no

Test material

Reference
Name:
Unnamed
Type:
Constituent

Test animals

Species:
rat
Strain:
Wistar
Sex:
male/female

Administration / exposure

Route of administration:
inhalation
Type of inhalation exposure (if applicable):
nose only

Results and discussion

Effect levels

open allclose all
Dose descriptor:
NOEC
Effect level:
172.5 mg/m³ air
Based on:
other:
Sex:
male/female
Remarks on result:
other:
Dose descriptor:
LOAEC
Effect level:
6.8 mg/m³ air
Based on:
other:
Sex:
male
Basis for effect level:
other:
Remarks on result:
other:

Applicant's summary and conclusion