Registration Dossier
Registration Dossier
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EC number: 203-973-1 | CAS number: 112-45-8
Long-term toxicity to fish
Administrative data
Link to relevant study record(s)
- Endpoint:
- long-term toxicity to fish
- Type of information:
- calculation (if not (Q)SAR)
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- accepted calculation method
- Justification for type of information:
- Data is from computational model developed by USEPA
- Qualifier:
- according to guideline
- Guideline:
- other: Modelling database
- Principles of method if other than guideline:
- Long term toxicity effect of test chemical on the mortality of fish.
- GLP compliance:
- no
- Analytical monitoring:
- no
- Vehicle:
- no
- Test organisms (species):
- other: Fish
- Test type:
- flow-through
- Water media type:
- freshwater
- Total exposure duration:
- 28 d
- Reference substance (positive control):
- no
- Key result
- Duration:
- 28 d
- Dose descriptor:
- NOEC
- Effect conc.:
- 0.213 mg/L
- Nominal / measured:
- estimated
- Conc. based on:
- test mat.
- Basis for effect:
- mortality
- Remarks on result:
- other: Neutral Organic SAR
- Validity criteria fulfilled:
- no
- Conclusions:
- The long term No Observed Effect Concentration (NOEC) for the test compound is estimated to be 0.213 mg/L.
- Executive summary:
Using the EPI Suite, the long term toxicity on fish was predicted for test substance. On the basis of no effects observed in a freshwater system, the no observed effect concentration (NOEC) value for the substance is estimated to be 0.213 mg/l for fish for 28 d duration.
Reference
Description of key information
Using the EPI Suite, the long term toxicity on fish was predicted for test substance. On the basis of no effects observed in a freshwater system, the no observed effect concentration (NOEC) value for the substance is estimated to be 0.213 mg/l for fish for 28 d duration.
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 0.213 mg/L
Additional information
Using the EPI Suite, the long term toxicity on fish was predicted for test substance. On the basis of no effects observed in a freshwater system, the no observed effect concentration (NOEC) value for the substance is estimated to be 0.213 mg/l for fish for 28 d duration.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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