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Ecotoxicological information

Toxicity to aquatic algae and cyanobacteria

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Description of key information

Toxicity to aquatic algae and cyanobacteria:
- EC50 (72h) = 23 mg/l (biomass) for Pseudokirchneriella subcapitata (OECD TG 201)
- EC10 (72h) = 5.8 mg/l (biomass) for Pseudokirchneriella subcapitata (OECD TG 201)
- NOEC (72h) = 4.5 mg/l (biomass) for Pseudokirchneriella subcapitata (OECD TG 201)
- EC50 (72h) = 53 mg/l (growth rate) for Pseudokirchneriella subcapitata (OECD TG 201)
- EC10 (72h) = 10 mg/l (growth rate) for Pseudokirchneriella subcapitata (OECD TG 201)
- NOEC (72h) = 4.5 mg/l (growth rate) for Pseudokirchneriella subcapitata (OECD TG 201)

Key value for chemical safety assessment

EC50 for freshwater algae:
53 mg/L
EC10 or NOEC for freshwater algae:
4.5 mg/L

Additional information

In a 72 hour acute toxicity study, the cultures of Pseudokirshneriella subcapitata were exposed to 11 -aminoundecanoic acid at nominal concentrations of 0 / 4.5 / 7.4 / 12.3 / 20.2 / 33.4 / 55.1 / 90.9 / 150 mg/L under static conditions in accordance with the OECD guideline 201.

Based on cell density 72h-NOEC=4.5 mg/L

72h-EC50= 23 mg/L

Based on growth rate 72h-NOEC=4.5 mg/L

72h-EC50 = 53 mg/L

Only a small abnormality was noted (turgid cells at concentrations of 150, 90.9 and 55.1 mg/L) but is not enought to invalidate the test.

As all validity criteria were fulfilled, OECD guideline and GLP requirements were followed and this study can be considered as valid without restriction.

Therefore, according to the Directive 67/548/EC, in the tested conditions 11 aminoundecanoic acid is considered as harmful for algae based on growth rate. However, the susbtance is not classified according to CLP criteria for algae.