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EC number: 215-252-9
CAS number: 1315-01-1
1. Body weight, Body weight change and Pre-terminal deaths
Body weight (g)
(Day 8 – Initial)
(Day 15 – Initial)
2. Short-Term And Long-Term Results
(mg/kg body weight)
The survival pattern used to determine whether and how to dose next
animal is a short term outcome.
The status of the animals at termination is the long term outcome.
3. Individual Clinical Signs and Necropsy Findings
Dose (mg/kg body weight)
No Abnormality Detected
An acute oral toxicity test (Up-and-Down Procedure)
was conducted with female Wistar rats to determine the potential of Tin
disulfide (CAS 1315-01-1). The test item was diluted in Milli-Q water
and administered as a single oral dose at 2000 mg/kg, first in one
female rat, followed by four additional animals at the same dose. Those
four animals survived, and the test was concluded. All animals were
active and gained body weight during 14 days observation period. All
animals were subjected to necropsy at sacrifice and there were no
abnormalities observed in any of the rats. Based on the present study
results, the estimated acute oral LD50 of Tin disulfide is greater than
2000 mg/kg body weight in female rats.
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