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EC number: 215-252-9
CAS number: 1315-01-1
of activated sludge respiration inhibition for tested material (1st
of activated sludge respiration inhibition for tested material
(additional test, directly weighing in):
The results are considered relevant
for tin disulfide since both substances have the same metal moiety and
have similar physico-chemical properties, e.g., they are almost
insoluble in water. Further evidence is provided in the read across
In the test for inhibition of
respiration of microorganisms by tin sulfide according to OECD 209 no
inhibition has been observed at any concentration, e.g., 11 µg/L and
1000 mg/L. Hence, tin sulfide has no inhibitoriy effect on the
microorganisms up to the water solubility.
Tin disulfide causes no inhibition of respiration of activated sludge. Determination of EC50 based on the obtained results was not possible. Based on the results obtained during additional test EC50 is above the highest nominal concentration – 1000 mg/L. This suspension was above water solubility level.
The endpoint was covered by read across
from tin sulfide.
Tin sulfide, at used concentrations, caused
no inhibition of respiration of activated sludge. Determination of EC50
based on the obtained results was not possible. Based on the results
obtained during additional test EC50 is above the highest nominal
concentration – 1000 mg/L. This suspension was above water solubility
Conclusion: Effects from tin
sulfide were only observed at concentrations higher than the water
solubility of tin sulfide (0.6 µg/L). Therefore, these effects are
considered as not relevant. Read across from tin sulfide to tin
disulfide was considered as possible (see Read Across justification
document attached to the dossier). Hence it can be concluded that
there is based on the read across data and the argumentation
provided for the read across, there is no risk at the limit of water
solubility of tin disulfide, i.e., at 0.67 µg/L.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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