Registration Dossier

Administrative data

Hazard for aquatic organisms

Freshwater

Hazard assessment conclusion:
no hazard identified

Marine water

Hazard assessment conclusion:
no hazard identified

STP

Hazard assessment conclusion:
no hazard identified

Sediment (freshwater)

Hazard assessment conclusion:
no hazard identified

Sediment (marine water)

Hazard assessment conclusion:
no hazard identified

Hazard for air

Air

Hazard assessment conclusion:
no hazard identified

Hazard for terrestrial organisms

Soil

Hazard assessment conclusion:
no data available: testing technically not feasible

Hazard for predators

Secondary poisoning

Hazard assessment conclusion:
no potential to cause toxic effects if accumulated (in higher organisms) via the food chain

Additional information

For tin disulfide an algal study is available. this study demonstrated that the tin sulfide has no toxic effects at the limit of water solubility, i.e., at 0.67 µg/L. The other aquatic endpoints were covered using data from tin sulfide which has an almost identical water solubility, i.e., 0.6 µg/L. The algal study was used as bridging study since the WHO concluded in their report that algae are the most sensitive group. Furthermore, the WHO concluded that Sn II is more toxic than Sn IV. Hence, read across from tin sulfide (Sn II) to tin disulfide (Sn IV) was considered justified.

The acute toxicity of tin sulfide to Gobiocypris rarus was conducted in accordance with OECD Guideline 203. Under valid static test conditions the 96 h-LL50 is greater than nominal tested concentration of 100 mg/L WAFs (measured concentration 0.014 mg/L).

The 13–day chronic toxicity of tin sulfide to early life stage of Brachydanio rerio was studied under semi-static conditions. Totally 60 embryos were exposed to measured tin sulfide concentrations up to 33 µg/L, which is the highest soluble fraction from a 100 mg/L (nominal) tin sulfide concentration. The test system was maintained at 23.9 to 25.8 ºC and a pH of 6.91 to 7.67.  The 13–day EC50value, based on mortality, was >33 µg a.i./L.  The sublethal effects included were hatching, weight and length of animals. The most sensitive end point was weight, the NOEC being 7 µg/L (equals to 12.5% of filtrate from soluble fraction of 100 mg/L).

The 21-day-chronic toxicity of tin sulfide to Daphnia magnawas studied under semistatic conditions. The sublethal effects included were reproduction output, reduction of parent growth and intrinsic rate. The most sensitive end point was reduction of reproduction output, the NOEC was 3 µg/L (equals 12.5 % of maximum soluble fration of nominal 20 mg/L).

EC50 (all endpoints): higher than 11.3 µg/L (equals to 100 % of maximum soluble fraction of nominal 20 mg/L).

In a 72-hour toxicity study, the cultures ofPseudokirchneriella subcapitatawere exposed to Tin sulfide at a measured concentration of 34 µg a.i./L, which was the soluble fraction from a nominal 100 mg/L tin sulfide concentration, under static conditions in accordance with the OECD 201 Guideline. No effects were observed, neither on growth rate, biomass reduction or changes in cell morphology.

In a test on respiration inhibition of activated sludge according to OECD 209, no effects were observed at a nominal concentration of 11 µg/L, which was prepared from a saturated solution in deionized water from nominal 100 mg/L tin sulfide. In an additional experiment, no effects were observed at concentrations up to 1000 mg/L directly weighed in.

Based on this information and the read across information it can be concluded that tin disulfide results in no acute and chronic effects up to the limit of water solubility, i.e., 0.67 µg/L.

Conclusion on classification

Based on the lack of acute or chronic effects at concentrations at or below the water solubility of tin disulfide no classification is needed according to EU Regulation 1272/2008 and 67/548 EEC.