Registration Dossier
Registration Dossier
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EC number: 907-745-9 | CAS number: -
Endpoint summary
Administrative data
Key value for chemical safety assessment
Additional information
Weight of evidence: Read-across approach from an analogue. The analogue CAS No. 128-37-0 (BHT) which shares the same functional group (alkylphenol) with the two main constituents of the substance Reaction mass of 2,6-di-tert-butylphenol and 2,4,6-tri-tert-butylphenol, also has comparable values for the relevant molecular properties. Therefore, the results obtained with the substance CAS No. 128 -37-0 can be used for the read-across approach. Based on in vitro and vivo experimental data, the read-across approach is applied and the substance is considered to be negative for genetic toxicity.
Justification for selection of genetic toxicity endpoint
No study was selected, since based on the in vitro and vivo experimental data, the read-across approach is applied and the substance is considered to be negative for genetic toxicity.
Short description of key information:
Weight of evidence: Read-across approach from an analogue.
The analogue CAS No. 128-37-0 (BHT) which shares the same functional group (alkylphenol) with the two main constituents of the substance Reaction mass of 2,6-di-tert-butylphenol and 2,4,6-tri-tert-butylphenol, also has comparable values for the relevant molecular properties. Therefore, the results obtained with the substance CAS No. 128 -37-0 can be used for the read-across approach.
Based on in vitro and vivo experimental data, the read-across approach is applied and the substance is considered to be negative for genetic toxicity.
Endpoint Conclusion: No adverse effect observed (negative)
Justification for classification or non-classification
Based on in vitro and vivo experimental data, the read-across approach is applied and the substance is considered to be negative for genetic toxicity. Therefore, the substance is not classified.
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