Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 218-915-0 | CAS number: 2280-49-1
Exposure related observations in humans: other data
Administrative data
- Endpoint:
- exposure-related observations in humans: other data
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Study period:
- 1971
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: limited doumentation; no guideline followed
Cross-reference
- Reason / purpose for cross-reference:
- reference to same study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 971
- Report date:
- 1971
Materials and methods
- Type of study / information:
- Human dermal exposure experiment to investigate potential irritation.
- Endpoint addressed:
- skin irritation / corrosion
Test guideline
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- The compound was applied to the forearm of 7 humans, respectively, by patching small cotton balls containing N-Phenyl-N-[(trichloromethyl)thio]benzenesulphonamide.
The patches were removed after 24 h and the skin was observed for a period of 7 days. No effects were observed at any time point. - GLP compliance:
- no
Test material
- Reference substance name:
- N-phenyl-N-[(trichloromethyl)thio]benzenesulphonamide
- EC Number:
- 218-915-0
- EC Name:
- N-phenyl-N-[(trichloromethyl)thio]benzenesulphonamide
- Cas Number:
- 2280-49-1
- Molecular formula:
- C13H10Cl3NO2S2
- IUPAC Name:
- N-phenyl-N-[(trichloromethyl)sulfanyl]benzenesulfonamide
- Test material form:
- other: solid
- Details on test material:
- no data on purity; the compound tested was 98% N-Phenyi-N-[(trichloromethyl)thio]benzenesulphonamide and 2% magnesium carbonate.
Constituent 1
Method
- Details on study design:
- The compound was applied to the forearm of 7 humans, respectively, by patching small cotton balls containing N-Phenyi-N-[(trichloromethyl)thio]benzenesulphonamide.
The patches were removed after 24 h and the skin was observed for a period of 7 days. No effects were observed at any time point. - Exposure assessment:
- not specified
Results and discussion
- Results:
- The compound was applied to the forearm of 7 humans, respectively, by patching small cotton balls containing N-Phenyl-N-[(trichloromethyl)thio]benzenesulphonamide.
The patches were removed after 24 h and the skin was observed for a period of 7 days. No effects were observed at any time point.
Applicant's summary and conclusion
- Executive summary:
The compound was applied to the forearm of 7 humans, respectively, by patching small cotton balls containing N-Phenyl-N-[(trichloromethyl)thio]benzenesulphonamide. The patches were removed after 24 h and the skin was observed for a period of 7 days. No effects were observed at any time point.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
