Registration Dossier
Registration Dossier
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EC number: 208-793-7 | CAS number: 541-85-5
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
Acute toxicity of 5-methylheptan-3-one (CASNr: 541-85-5) to goldfish (Carassius auratus) was tested in a 24 h study period. LC50 after 24 h was 80 mg/l. The result was confirmed by an estimation of a 96 h LC50 using Ecosar calculation (LC50 (96h) 77.7 mg/l). In addition, a LC50 after 96h of 428mg/l was measured for the read across substance 2-hexanone (Geiger D.L. et al., 1986: Acute toxicities of organic chemicals to Fatheas Minnows (Pimephales promelas) Volume III, ISBN 0-9614968-2-7).
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 80 mg/L
Additional information
Acute toxicity of 5-methylheptan-3-one (CASNr: 541-85-5) to goldfish (Carassius auratus) was tested in a 24 h study period. LC50 after 24 h was 80 mg/l. The result was confirmed by an estimation of a 96 h LC50 using Ecosar calculation (LC50 (96h) 77.7 mg/l). The result was also 5 times lower than the LC50 (96h) measured for the read across substance 2-hexanone (1). Based on these data in combination with the fact that the substance is readily biodegradable, a classification is not required.
(1) Geiger D.L., Poirier S.H., Brooke L.T., Call D.J., eds. Acute Toxicities of Organic Chemicals to Fathead Minnows (Pimephales Promelas). Vol. III. Superior, Wisconsin: University of Wisconsin-Superior, 1986., p. 139
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