2,2-dimethyl-1,3-dioxolan-4-ylmethanol

Boiling point

Link to relevant study record(s)

Reference

Endpoint:

boiling point

Type of information:

experimental study

Adequacy of study:

key study

Study period:

From 16 September 2013 to 6 November 2013

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

other: GLP study performed according international guidelines. A deviation from the guidelines do not affect the results of the study was observed.

Qualifier:

according to guideline

Guideline:

OECD Guideline 103 (Boiling point/boiling range)

Deviations:

yes

Remarks:

(A temperature-controlled metal heating block was used instead of a liquid bath. This deviation have no effect on the results of the study.)

Qualifier:

according to guideline

Guideline:

EPA OPPTS 830.7220 (Boiling Point / Boiling Range)

Deviations:

yes

Remarks:

(A temperature-controlled metal heating block was used instead of a liquid bath. This deviation have no effect on the results of the study.)

GLP compliance:

yes

Type of method:

method according to Siwoloboff

Key result

Boiling pt.:

192.3 °C

Atm. press.:

1 atm

Decomposition:

no

Instrument performance was verified through the use of reference standards. All reference substances provided acceptable results.

Reference Standard	Instrument Gradient (°C/min)	Recorded Melting point (°C)	Average	Expected Melting Point/Range(°C)
Caffeine	1.0	237.0	237.0	237
Anthraquinone	1.0	285.4	285.2	284-286
		285.1
		285.4
Benzophenone	1.0	49.1	49.2	49-51
		49.3
		19.3

A boiling point approximation test (Rapid Scan) did result in a measurable boiling point of 190°C (463 K) and a boiling range of 77.0 (350 K) to 190°C (463 K). These results were used to determine the range of temperatures used in the definitive test.

During the definitive testing the test substance samples provided a mean boiling point of 192.5± 0.2°C and a mean boiling range from 72.5°C (346 K) to 192.5°C (466 K) for the three tests.

At room temperature, the test substance was clear and colorless. Upon removal from the instrument (at test termination), the test substance was clear but light-tan in color. Results of the corrected boiling point determinations for the test substance are presented in the following table:

Subsample ID	Instrument Gradient (°C/min)	Barometric Pressure (kPa)	Start of Boiling range °C(K) *	End of Boiling Range °C (K)	Boiling Point °C (K)
411C-104-1	1.0	102	72.7 (345.8)	192.1 (465.2)	192.1 (465.2)
411C-104-2	1.0	102	72.3 (345.4)	192.4 (465.5)	192.4 (465.5)
411C-104-3	1.0	102	72.0 (345.2)	192.3 (465.4)	192.3 (465.4)
Overall Means :		102	72.3 (346)	192.3 (465)	192.3 (465)
Standard Deviations :		0	0.3 (0.3)	0.2 (0.2)	0.2 (0.2)
CV (%) :		0.0	0.44 (0.1)	0.08 (<0.1)	0.08 (<0.1)

* K = 273.15 + °C

Conclusions:

The test substance sample provided a mean normal boiling point of 192.3 ± 0.2°C (465 ± 0.2 K) and a mean normal boiling range from 72.3°C (346 K) to 192.3°C (465 K).

Executive summary:

The boiling point was determined according to U.S EPA Product Test Guidelines, OPPTS 830.7220, OECD guideline 103 and GLP. A modification of Siwoloboff procedure described in OECD Guideline N°103 was used in the study. This deviation did not affect the quality of the study.

Before the determination of the test substance boiling point, three references standards (caffeine, benzophenone and anthraquinone) were used to check the accuracy of the apparatus across a range of temperatures (Büchi Melting Point B-540 instrument). The three reference substance provide acceptables results. The apparatus was considered acceptable for use according to the results obtained with the references standards.

The boiling point determination was performed from 50.0 to 195ºC at a rate of 1.0ºC per minute. The temperature at which a steady stream of bubbles was observed emerging from the open end of a capillary submerged in the test substance was recorded and accepted as the boiling point. The boiling range was defined as the region between the first emergence of bubbles from the capillary tube and the emergence of a steady stream of bubbles. The barometric pressure was recorded at the time measurements were made. The test substance sample provided a mean normal boiling point of 192.3 ± 0.2°C (465 ± 0.2 K) and a mean normal boiling range from 72.3°C (346 K) to 192.3°C (465K).

Description of key information

Experimental boiling point at 101 kPa: 192.3 °C +/-0.2°C
Experimental boiling range at 101kPa: 72.3 to 192.3°C  

Key value for chemical safety assessment

Boiling point at 101 325 Pa:

192.3 °C

Additional information

The boiling point was determined according to U.S EPA Product Test Guidelines, OPPTS 830.7220, OECD guideline 103 and GLP. A modification of Siwoloboff procedure described in OECD Guideline N°103 was used in the study. This deviation did not affect the quality of the study. The apparatus was considered acceptable for use according to the results obtained with references standards.