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Ecotoxicological information

Toxicity to birds

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Description of key information

Two avian acute toxicity tests were conducted with EDHO according the protocols consistent with standard test guidelines.
The first test was an acute oral test with northern bobwhite (Colinus virginanus) designed to determine the LD50 of EDHO. Adult birds were exposed to a single oral dose of the test material, then observed for 21 days post-exposure. Based on this single oral dose, the LD50 of EDHO to northern bobwhite was determined to be 1100 mg a.i./kg body weight.
The second test was an acute dietary test with northern bobwhite (Colinus virginanus) designed to determine the LC50 of EDHO (similar to OECD 205). Ten-day-old birds were exposed to concentrations of EDHO mixed in with avian diet for five days then monitored for an additional three days after a switch to untreated feed. Based on this exposure, the LC50 of EDHO to northern bobwhite was determined to be >5000 mg a.i./kg diet.

Key value for chemical safety assessment

Short-term EC50 or LC50 for birds:
5 000 mg/kg food

Additional information

Two acute avian tests were conducted with EDHO according to protocols similar to standard test guidelines. The first test was an acute oral test with northern bobwhite (Colinus virginanus) designed to determine the LD50 of EDHO. The second test was an acute dietary test with northern bobwhite (Colinus virginanus) designed to determine the LC50 of EDHO (similar to OECD 205). 

 

In the acute oral test adult birds were exposed to a single oral dose of the test material, then observed for 21 days post-exposure. Based on this single oral dose, the LD50 of EDHO to northern bobwhite was determined to be 1100 mg a.i./kg body weight.   Ten-day-old birds were exposed to concentrations of EDHO mixed in with avian diet for five days then monitored for an additional three days after a switch to untreated feed. Based on this exposure, the LC50 of EDHO to northern bobwhite was determined to be >5000 mg a.i./kg diet.

 

These results of the avian acute tests indicate that EDHO would be classified as not dangerous to avian species on an acute basis.