Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 268-018-3 | CAS number: 67989-88-2
Toxicity to soil macroorganisms except arthropods
Administrative data
Link to relevant study record(s)
Description of key information
One acute toxicity test with earthworms according to TG OECD 207 is available with an EDTA-Cu complex (i.e. EDTA-CuK2). This test from Winkelmann resulted in a NOEC forbody weight loss of 316 mg/kg soil dry weight and LOEC was determined to be 1000 mg/kg soil dry weight. The active ingredient content of the EDTA-CuK2 batch was 92%. The NOEC and LOEC based on active ingredient are then 291 and 920 mg EDTA-CuK2 /kg dw. Corrected for the MW difference between EDTA-CuK2 and EDTA-Cu(NH4)2 this results in a NOEC (291 *387.8.3/430) = 262.4 and LOEC of 830 mg a.i./kg dw.
As reference there one acute toxicity study with earthworms is available for EDTA-H4 (Edwards, 2009). The EC50 was determined at 156 mg/kg soil dry weight.
This corresponds to 212 mg/kg soil dw EDTA-Cu(NH4)2.
The study results from Winkelmann will be, based on the higher quality, used for the terrestrial hazard assessment.
Key value for chemical safety assessment
- Short-term EC50 or LC50 for soil macroorganisms:
- 262.4 mg/kg soil dw
Additional information
The hazard assessment of EDTA-Cu(NH4)2 reveals neither a need to classify the substance as dangerous to the environment, nor is it a PBT or vPvB substance. The substance is expected to have a low potential for adsorption based on its ionic structure under environmental relevant pH conditions and its low log Kow , the low log Kow also indicates that the substance will not be bioaccumulative. There are no further indications that the substance may be hazardous to the environment.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
