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Physical & Chemical properties

Melting point / freezing point

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Reference
Endpoint:
melting point/freezing point
Type of information:
experimental study
Adequacy of study:
key study
Study period:
1999-06-14 to 1999-08-07
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Remarks:
The study was conducted according to an internationally recognised method, and under GLP. Purity and isomers composition are available from the notifier. Therefore full validation applies.
Qualifier:
according to
Guideline:
EU Method A.1 (Melting / Freezing Temperature)
Qualifier:
according to
Guideline:
other: BS 4633
GLP compliance:
yes (incl. certificate)
Remarks:
UK GLP compliance programme (inspected on 23rd March 1998/ signed on 21st July 1998)
Type of method:
method to determine freezing temperature
Specific details on test material used for the study:
Storage condition of test material: room temperature, in the dark, under nitrogen.
Key result
Melting / freezing pt.:
< 253 K

Observations: the test material became slightly viscous on being cooled.

Accuracy is not specified.

Conclusions:
No further testing is required (< -20°C).
Executive summary:

The crystallizing point of the test substance was determined under GLP according to BS4633 method (listed in EU A1 guideline).

Two runs were performed.

Only slight increase in viscosity of the test material was observed down to a temperature of 253 K (-20°C).

Description of key information

Freezing point < -20 °C

No further testing is required.

Key value for chemical safety assessment

Additional information

A fully reliable experimental study, conducted according to a recognized EC method and under GLP, is available. Therefore, it is considered as a key study. As no crystallisation was observed down to -20°C, the result is expressed as a limit value, and cannot be retained as key data for purpose of CSA.