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Physical & Chemical properties

Partition coefficient

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Reference
Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Study period:
23 March 2012 - 29 August 2012
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to
Guideline:
EU Method A.8 (Partition Coefficient)
Deviations:
no
Qualifier:
according to
Guideline:
OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)
Deviations:
no
GLP compliance:
yes (incl. certificate)
Type of method:
HPLC method
Partition coefficient type:
octanol-water
Analytical method:
high-performance liquid chromatography
Key result
Type:
log Pow
Partition coefficient:
1.5
Temp.:
25 °C
Remarks on result:
other: Unbuffered mobile phase
Details on results:
- Details of fitted regression line: log Pow = 3.60 log k + 3.14
- The chromatogram of the test item showed one peak (retention time: 1.837 minutes).
Conclusions:
BMI was found to have a log10Pow value of 1.5. The corresponding Pow is 31.

Description of key information

The log Pow of BMI was found to be 1.5.

Key value for chemical safety assessment

Log Kow (Log Pow):
1.5
at the temperature of:
25 °C

Additional information

as determined using the HPLC method