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Toxicological information

Acute Toxicity: oral

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Administrative data

Endpoint:
acute toxicity: oral
Type of information:
experimental study
Adequacy of study:
weight of evidence
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Data have been obtained from secondary source.

Data source

Referenceopen allclose all

Reference Type:
secondary source
Title:
No information
Author:
Hazardous Substances Data Bank (HSDB)
Year:
2012
Bibliographic source:
Hazardous Substances Data Bank (HSDB)
Reference Type:
review article or handbook
Title:
No information
Author:
National Research Council.
Year:
1981
Bibliographic source:
Drinking Water & Health, Volume 4. Washington, DC: National Academy Press., p. 236, 1981

Materials and methods

Principles of method if other than guideline:
The method has not been specified.
GLP compliance:
not specified

Test material

Reference
Name:
Unnamed
Type:
Constituent

Test animals

Species:
dog
Strain:
not specified
Sex:
not specified

Administration / exposure

Route of administration:
oral: unspecified
Vehicle:
not specified
Doses:
20 to 30 mg/kg

Results and discussion

Effect levels
Sex:
not specified
Dose descriptor:
LD50
Effect level:
ca. 20 - 30 other: mg/kg

Any other information on results incl. tables

The lethal dose LD50 on dog is 20 to 30 mg/kg. This value has been taken from table. Details of toxic effects have not been reported other than lethal dose value.

Applicant's summary and conclusion

Conclusions:
The acute oral toxicity test defined a lethal dose LD50 on cat of 20 - 30 mg/kg, but details of toxic effects have not been reported other than lethal dose value. This value has been taken from table.
Executive summary:

Data have been obtained from secondary source that mentions National Research Council. Drinking Water & Health, Volume 4. Washington, DC: National Academy Press, 1981., p. 236. The method used has not been specified and data have been taken from table.

The lethal dose LD50 on dog is 20 to 30 mg/kg, but details of toxic effects have not been reported other than lethal dose value.