Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 238-270-9
CAS number: 14324-55-1
The value of 3.2 µg/L derived in the 21-day toxicity study in Daphnia magna is considered to be a NOEC and used in the risk assessment.
One long-term toxicity study with
Daphnia magna is available for the test substance. The test is a
semi-static non-GLP, pre-guideline 21-day reproduction study with
neonate (<24 h) Daphnia magna, without analytical monitoring (van
Leeuwen et al., 1985c). At least five concentrations (with a ratio of
1.8) were tested in five-fold including a blank control. Ten daphnids
were used for each replicate sample. The test solutions were renewed
three times a week and were prepared fresh at each renewal. The number
of surviving females and number of neonates were recorded daily, the
neonates being removed from the test vessels after counting. The
survival pattern of the daphnids was clearly related to the exposure
concentration and a gradual decline of the LC50 with time was observed.
Generally, the lower rate of population increase caused by certain
concentrations of test compounds was due to both increased mortality and
fewer clutches per female. The latter was also due to reduced parental
survival. The LRCT (lowest rejected concentration tested; similar to the
LOEC) was 10 µg/L. The NOEC was derived from the LOAEC by applying a
factor of 1.8, resulting in a value of ≤ 3.2 µg/L.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
Welcome to the ECHA website. This site is not fully supported in Internet Explorer 7 (and earlier versions). Please upgrade your Internet Explorer to a newer version.
Do not show this message again