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EC number: 208-760-7
CAS number: 540-88-5
In a reverse gene mutation assay in bacteria, strains TA 98, TA 100, TA
102, TA 1535 and TA 1537 of S. typhimurium and strain WP2 uvr A pKM 101
of E. coli were exposed to tertiary butyl acetate in DMSO at
concentrations of 5, 15, 50, 150, 500, 1500 and 5000 µg/plate in the
presence and absence of mammalian metabolic activation using the plate
incorporation method. Tertiary butyl acetate was tested up to the limit
concentration of 5000 μg/plate. There was a reduction in the number of
mutant colonies and a thinning of the background lawn of micro-colonies,
indicative of toxicity, at 5000 μg/plate. The positive controls induced
the appropriate responses in the corresponding strains. There was no
evidence of induced mutant colonies over background.
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