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EC number: 208-760-7
CAS number: 540-88-5
The potential for tertiary butyl acetate to
cause dermal sensitization is well understood. In
the key study, a Buehler test conducted according to EPA OPP Guideline
81-6, a concentration of 100% tertiary butyl acetate at challenge did
not cause a sensitization reaction in ten male guinea pigs previously
induced with three separate six-hour epicutaneous, occlusive exposures
performed once per week for three weeks.
No evidence of a sensitization response was observed in a guideline
dermal sensitization study conducted in guinea pigs. Tertiary butyl
acetate is not classified for dermal sensitization according to EU CLP
(Regulation (EC) No. 1272/2008) and UN GHS.
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