Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 208-760-7
CAS number: 540-88-5
All rabbits (6/6) were graded as "0" for edema at the 1-, 24 -, 48 -,
and 72-hour examinations. Four of six rabbits (4/6) showed minimal
erythema (score of 1) at the 24-hour observation period while 2/6
rabbits were normal. All rabbits were graded as "0" for erythema at the
48- and 72-hour examinations.
In a primary dermal irritation study, young adult New Zealand white
rabbits (3 males, 3 females) were exposed to 0.5 mL of tertiary butyl
acetate applied for 4 hours under semi-occlusive contact to intact skin.
Animals were then observed for 72 hours. Irritation was scored by the
method of Draize. No edema was noted. The test material caused minimal
erythema at 1 and 24 hours in some rabbits but no signs of erythema were
present at the 48- or 72-hour observation periods. Tertiary butyl
acetate is not considered a dermal irritant under conditions of this
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
Welcome to the ECHA website. This site is not fully supported in Internet Explorer 7 (and earlier versions). Please upgrade your Internet Explorer to a newer version.
Do not show this message again