2-(2-butoxyethoxy)ethyl 6-propylpiperonyl ether

Additional information on environmental fate and behaviour

Administrative data

Endpoint:

additional information on environmental fate and behaviour

Adequacy of study:

supporting study

Study period:

1991

Reliability:

1 (reliable without restriction)

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

1991

Report date:

1991

Materials and methods

Principles of method if other than guideline:

EPA Guideline, Subdivision N, Section 162-4

GLP compliance:

yes

Test material

Test material information

Constituent 1

Reference substance name:

2-(2-butoxyethoxy)ethyl 6-propylpiperonyl ether

EC Number:

200-076-7

EC Name:

2-(2-butoxyethoxy)ethyl 6-propylpiperonyl ether

Cas Number:

51-03-6

Molecular formula:

C19H30O5

IUPAC Name:

2-(2-butoxyethoxy)ethyl 6-propylpiperonyl ether

Results and discussion

Any other information on results incl. tables

Recovery:
Overall recovery decreased from 96.8 % of the applied radioactivity,  initially, to 83.8 % after 30 days.

Mineralization:
After 30 days of incubation, 0.122 % of the applied radioactivity present  in the KOH traps was shown to be 14CO2. 

Parent compound:
Parent compound accounted for 83.8 % of the applied radioactivity at the  study's termination. The level of Piperonyl Butoxide in water amounted to  44 % at day 0 and 53 % at day 1. 32 % was detected after 30 days of  application. The level of Piperonyl Butoxide in the sediment decreased  from 53 % of applied radioactivity, initially, to 52 % after 30 days.

Metabolites:
Altogether 3 possible metabolites could be observed during the TLC  analysis of water and soil extracts. None exceeded 10 % of applied  radioactivity. One degradate, which had a maxima of 7.1 % at day 14, was  qualitatively identified as one component and named Metabolite F  (Origin). A slightly increase of two further metabolites could be  observed, but not identified. They were named Unknown 1 (Intermediate II,  Rf = 0.05) and Unknown 2 (Intermediate I, Rf = 0.1).

Proposed degradation pathway: 
Parent compound > Intermediate I > Intermediate II > Metabolite F > 14CO2  + Non-extractable residues.

Degradation kinetics:
The half-life of Piperonyl Butoxide under aerobic aquatic conditions was  calculated to be 109 days by using first-order kinetics. The kinetic  constant for the degradation was obtained from the linear regression  analysis of the plot of ln percent applied 14C-Piperonyl Butoxide versus  days (y = -0.00638 x + 4.60, r = -0.899).

Microbial viability:
The plate count analysis showed a slightly decrease of the bacterial but  not of the fungal colonies.

t1/2 at pH: 6.8 = 109 day(s) at 25 °C

Applicant's summary and conclusion

Conclusions:

The results indicate that 14C-Piperonyl Butoxide was not significantly degraded in the aerobic aquatic metabolism study. The level of none degradation product exceeded 10 % of the applied radioactivity.