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Diss Factsheets
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EC number: 952-967-1 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Dissociation constant
Administrative data
Link to relevant study record(s)
- Endpoint:
- dissociation constant
- Remarks:
- Solublity in acid
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Study period:
- 1 hour contact time
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- study well documented, meets generally accepted scientific principles, acceptable for assessment
- Justification for type of information:
- It is not considered possible to perform standard dissociation constant methods in view of the initial reported water solublity < 1 mg/l.
In addition, the substance will dissociate and hydrolyse resulting in an irreversible process to form stable poorly soluble salts (oxide) of titananium and water soluble salts of sodium. A speciflc method was devised to measure formation of water soluble salts. - Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- The substance was mixed in distilled water and in molar HCl. After mixing for one hour at room temperature, the liquids were filtered and washed to leave a clear filtrate and residual solid on the filters. The filtrates were dried to determine if any soluble fractions and the solids formed from solution were weighed to give an approximate quantitative result.
- GLP compliance:
- no
- Dissociating properties:
- yes
- Remarks on result:
- not determinable because of methodological limitations
- Remarks:
- The presence of soluble fractions implies dissociation, but pKa not determined.
- Conclusions:
- This experiment indicates that there is formation of soluble salts from mixing in excess acid or mixing in dilute forms in distilled water.
Soluble salts will form through dissociation of inorganic ions and in this case, the process is made irreversible through the formation of the stable titanium oxide
This experiment indicates that there is formation of soluble salts from mixing in excess acid or mixing in dilute forms in distilled water.
In terms of Na solubility, loading at 1000 mg/l resulted in ca 120 mg Na (300 mg NaCl) when mixed in acid and ca 120 mg Na (200 mg NaOH) in deionised water. It is assumed that a trace of Ti will have passed through filters, but with reported Ti solubility < 1 mg/l, this will be negligible.
Reference
As expected, both mixtures remained cloudy with a large amount of undissolved material, but when filtering and then evaporating the filtrate, some solid residues crystallised out of solution. The amount of solid formed was significantly higher in the acid-treated mixture, but some solids formed even with distilled water at pH10.
100 mg of sodium titanate mixed in 100 ml of distilled water or 1M HCl at 20 C resulted in 20 mg and 30 mg of solid crystallising from filtrate respectively; the acid treatment clearly led to a higher yield, suggesting more dissociation. However, even the 20 mg formed with distilled water implied some degradation.
In terms of Na solubility, loading at 1000 mg/l resulted in ca 120 mg Na (300 mg NaCl) when mixed in acid and ca 80 mg Na (200 mg NaCl) in deionised water. It is assumed that a trace of Ti will have passed through filters, but with reported Ti solubility < 1 mg/l, this will be negligible.
Further work is needed to identify the solid residues on the filter and crystallising from the filtrate. It is also considered important to work on environmentally relevant concentrations to determine if the rate of dissociation / hydrolysis is faster and/or more complete.
The proposed reaction scheme is:
Na2O3Ti + 2HCl dissociates and leads to 2NaCl + TiO3H2 and in turn 'hydrolyses' to TiO2 + H2O + 2NaCl
Theoretical yield of NaCl from 0.1 g sodium titanate (0.0007 moles) with excess 0.1 mole hydrochloric acid is ca 80 mg
Description of key information
The proposed reaction scheme is:
Na2O3Ti + 2HCl goes to 2NaCl + TiO3H2 which in turn hydrolyses to TiO2 + H2O + 2NaCl
Theoretical yield of NaCl from 0.1 g sodium titanate (0.0007 moles) with excess 0.1 mole hydrochloric acid is ca 80 mg
It is also noted from analysis (XRD) that the material tested contains a significant level of TiO2, therefore reducing apparent yield.
This experiment indicates that there is formation of soluble salts from mixing in excess acid or mixing in dilute forms in distilled water.
Soluble salts will form through dissociation of inorganic ions and in this case, the process is made irreversible through the formation of the stable titanium oxide
Key value for chemical safety assessment
Additional information
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