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EC number: 947-407-8 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
- Remarks:
- Data is for read across substance
- Justification for type of information:
- Data for the target chemical is summarized based on the structurally similar read across chemicals
- Reason / purpose for cross-reference:
- read-across source
- Reason / purpose for cross-reference:
- read-across source
- Reason / purpose for cross-reference:
- read-across source
- Qualifier:
- according to guideline
- Guideline:
- other: As mention below
- Principles of method if other than guideline:
- WoE report is based on three short term toxicity study of invertebrate for the test chemical :
- GLP compliance:
- not specified
- Specific details on test material used for the study:
- - Name of test material : Reaction mass of Benzenamine, N,N-dimethyl- , molybdate, tungstate & phosphates - Substance type: Organic- Physical state: Solid- Physical Appearance: Violet powder
- Analytical monitoring:
- not specified
- Vehicle:
- not specified
- Test organisms (species):
- Daphnia magna
- Details on test organisms:
- 3. Details on test organismsTEST ORGANISM- Common name: water flea - Age at study initiation (mean and range, SD):< 24 h (hour(s))Life Stage: JV (juvenile(s))
- Test type:
- static
- Water media type:
- freshwater
- Total exposure duration:
- 48 h
- Test temperature:
- 3. 8 degree C
- Details on test conditions:
- 3. - No. of organisms per vessel: 5 daphnia magna
- Reference substance (positive control):
- not specified
- Key result
- Duration:
- 48 h
- Dose descriptor:
- EC50
- Effect conc.:
- 0.28 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Remarks on result:
- other: Toxic from 1 study
- Key result
- Duration:
- 48 h
- Dose descriptor:
- EC50
- Effect conc.:
- 0.27 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Remarks on result:
- other: For 2 study chemical was consider as toxic
- Key result
- Duration:
- 48 h
- Dose descriptor:
- EC50
- Effect conc.:
- 0.072 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
- Remarks on result:
- other: For 3rd study
- Validity criteria fulfilled:
- not specified
- Conclusions:
- 1. Based on the mobility of daphnia magna by the test chemical, the effective concentration EC50 to 50% of daphnia magna for test chemical was determine to be 0.28 mg/l at 48 hr. From EC50, It can be concluded that the chemical was toxic to the aquatic invertebrate.2. Study was conducted for 48 hrs and after that immobility was observed. Based on the immobility the EC50 was determine to be 0.27 mg/l.3. After the exposure of 48 hrs immobility was observed in 50 % test organisms. The EC50 value for chemical was determined to be 0.072 mg/l. Based on the value the substance concluded to be toxic and can be considered to be classified in aquatic acute 1 as per the CLP regulations.Based on above experimental studies it was concluded that the reaction mass of Benzenamine, N,N-dimethyl- , molybdate, tungstate & phosphates was toxic and classified as aquatic acute 1 and chronic 1 as per the CLP criteria.
- Executive summary:
Summarized result for data available for the structurally and functional similar read across chemicals study has been reviewed to determine the toxicity of the test reaction mass of Benzenamine, N,N-dimethyl- , molybdate, tungstate & phosphates on the growth of aquatic invertebrates. The studies are as mentioned below:
In study 1 short term toxicity test was carried out for test chemical according to the OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test) on Daphnia magna for 48 hr exposure period. Test conducted under the static system and provide proper atmosphere as mention in the guideline. Based on the mobility of daphnia magna by the test chemical, the effective concentration EC50 to 50% of daphnia magna for test chemical was determine to be 0.28 mg/l at 48 hr. From EC50, It can be concluded that the chemical was toxic to the aquatic invertebrate and thus can be considered to be classified in aquatic acute category 1 as per the classification criteria.
First study was supported by second in which aim of this study was to evaluate the nature of chemical when comes in contact with organisms by providing the exposure period of 48 hrs. Test conducted under the static system. Study was conducted for 48 hrs and after that immobility was observed. Based on the immobility the EC50 was determine to be 0.27 mg/l. Based on the immobility, chemical was concluded as toxic and classified as aquatic acute 1/ chronic 2 as per the CLP criteria.
Similarly in third study short term toxicity to aquatic invertebrates was performed in static salt water condition for 48 hrs. <24 hrs old daphnia were used as a test organism. Test conducted under the static system in which 5 daphnia added in each vessel. After the exposure of 48 hrs immobility was observed in 50 % test organisms. The EC50 value for chemical was determined to be 0.072 mg/l. Based on the value the substance concluded to be toxic and can be considered to be classified in aquatic acute 1 as per the CLP regulations.
Based on above experimental studies it was concluded that the reaction mass of Benzenamine, N,N-dimethyl- , molybdate, tungstate & phosphates was toxic and classified as aquatic acute 1 and chronic 1 as per the CLP criteria.
Reference
Description of key information
1. Based on the mobility of daphnia magna by the test chemical, the effective concentration EC50 to 50% of daphnia magna for test chemical was determine to be 0.28 mg/l at 48 hr. From EC50, It can be concluded that the chemical was toxic to the aquatic invertebrate.
2. Study was conducted for 48 hrs and after that immobility was observed. Based on the immobility the EC50 was determine to be 0.27 mg/l.
3. After the exposure of 48 hrs immobility was observed in 50 % test organisms. The EC50 value for chemical was determined to be 0.072 mg/l. Based on the value the substance concluded to be toxic and can be considered to be classified in aquatic acute 1 as per the CLP regulations.
Based on above experimental studies it was concluded that the reaction mass of Benzenamine, N,N-dimethyl- , molybdate, tungstate & phosphates was toxic and classified as aquatic acute 1 and chronic 1 as per the CLP criteria.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 0.28 mg/L
Additional information
Summarized result for data available for the structurally and functional similar read across chemicals study has been reviewed to determine the toxicity of the test Reaction mass of Benzenamine, N,N-dimethyl- , molybdate, tungstate & phosphates on the growth of aquatic invertebrates. The studies are as mentioned below:
In study 1 short term toxicity test was carried out for test chemical according to the OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test) on Daphnia magna for 48 hr exposure period. Test conducted under the static system and provide proper atmosphere as mention in the guideline. Based on the mobility of daphnia magna by the test chemical, the effective concentration EC50 to 50% of daphnia magna for test chemical was determine to be 0.28 mg/l at 48 hr. From EC50, It can be concluded that the chemical was toxic to the aquatic invertebrate and thus can be considered to be classified in aquatic acute category 1 as per the classification criteria.
First study was supported by second in which aim of this study was to evaluate the nature of chemical when comes in contact with organisms by providing the exposure period of 48 hrs. Test conducted under the static system. Study was conducted for 48 hrs and after that immobility was observed. Based on the immobility the EC50 was determine to be 0.27 mg/l. Based on the immobility, chemical was concluded as toxic and classified as aquatic acute 1/ chronic 2 as per the CLP criteria.
Similarly in third study short term toxicity to aquatic invertebrates was performed in static salt water condition for 48 hrs. <24 hrs old daphnia were used as a test organism. Test conducted under the static system in which 5 daphnia added in each vessel. After the exposure of 48 hrs immobility was observed in 50 % test organisms. The EC50 value for chemical was determined to be 0.072 mg/l. Based on the value the substance concluded to be toxic and can be considered to be classified in aquatic acute 1 as per the CLP regulations.
Based on above experimental studies it was concluded that the reaction mass of Benzenamine, N,N-dimethyl- , molybdate, tungstate & phosphates was toxic and classified as aquatic acute 1 and chronic 1 as per the CLP criteria.
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