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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
hydrolysis
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: Guideline study and GLP

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2013
Report date:
2013

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 111 (Hydrolysis as a Function of pH)
GLP compliance:
yes (incl. QA statement)

Test material

Results and discussion

Transformation products:
no
Total recovery of test substance (in %)
% Recovery:
82 - 108
Dissipation DT50 of parent compoundopen allclose all
Key result
pH:
4
Temp.:
20 °C
Hydrolysis rate constant:
2.118 h-1
DT50:
0.3 h
Key result
pH:
7
Temp.:
20 °C
Hydrolysis rate constant:
0.018 h-1
DT50:
38.7 h
Key result
pH:
9
Temp.:
20 °C
Hydrolysis rate constant:
0.005 h-1
DT50:
138.6 h

Applicant's summary and conclusion

Validity criteria fulfilled:
yes
Conclusions:
The test item is hydrolytically unstable at pH4, pH7 and pH9
Executive summary:

The test item is hydrolytically unstable at pH4, pH7 and pH9