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EC number: 306-361-3 | CAS number: 97158-31-1
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- November 5, 1992- December 3, 1992
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study with acceptable restrictions
- Remarks:
- The test treatments were conducted using single replicates, guideline stipulates duplicate treatments
- Justification for type of information:
- Refer to section 13 of IUCLID for details on the read-across justification. The study with the read across substance is considered sufficient to fulfil the information requirements as further explained in the provided endpoint summary.
- Reason / purpose for cross-reference:
- read-across source
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 B (Ready Biodegradability: CO2 Evolution Test)
- Version / remarks:
- The test treatments were conducted using single replicates, guideline stipulates duplicate treatments.
- GLP compliance:
- yes (incl. QA statement)
- Specific details on test material used for the study:
- - Name of test material (as cited in study report): diethyl ester dimethyl ammonium chloride (E 4607.01)
- Substance type: pure act. ingr. substance
- Physical state: liquid, A 5 % dispersion (E 4607.01) of DEEDMAC was prepared for dosing the test system using the parent test chemical E 4429.01.
- Preparation of Dispersion solution : 5% aqueous dispersion of DEEDMAC made up in 3.7% HCl Solution (pH 2.6)
- Stability under test conditions: yes
- Storage condition of test material: rt - Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic, non-adapted
- Details on inoculum:
- The sludge was treated with a mechanical blender and allowed to settle for ~30 minutes. The supernatant was decanted from the settled sludge and used as inoculum at the rate of 10 ml/L of mineral media
- Duration of test (contact time):
- ca. 28 d
- Initial conc.:
- ca. 10 mg/L
- Based on:
- DOC
- Initial conc.:
- ca. 20 mg/L
- Based on:
- other: measured TOC of stock solution
- Parameter followed for biodegradation estimation:
- CO2 evolution
- Parameter followed for biodegradation estimation:
- TOC removal
- Details on study design:
- A 301B screening test was run using the following test treattments:
single replicate of the reference compound, Aniline and a single 10 and 20 mg/L test material treatment (E 4607.01)
3L of media was prepared for each treatment as described in the OECD 301 guideline. The inoculum was added to media at a concentration of 10mlL.THe mixture was aerated with CO2 free air for 24 hr to purge the system of CO2. The media containers were connected to 100 ml BaOH2 trapping train. The train is operated by bubbling CO2 free air through the solutions.
The CO2 collected in the BaOH2 traps was titrated with 0.05 N HCL. At the end of the test, the pH of the media was measured and 1 ml of HCL was added to each flask to drive off inorganic carbonate. After overnight incubation, 100 ml sampels were removed for organic carbon analysis. - Reference substance:
- aniline
- Key result
- Parameter:
- % degradation (CO2 evolution)
- Value:
- ca. 76
- Sampling time:
- 28 d
- Remarks on result:
- other: 10 mg/L conc.
- Key result
- Parameter:
- % degradation (CO2 evolution)
- Value:
- ca. 79
- Sampling time:
- 28 d
- Remarks on result:
- other: 20 mg/L conc.
- Key result
- Parameter:
- % degradation (TOC removal)
- Value:
- ca. 79
- Sampling time:
- 28 d
- Remarks on result:
- other: 10 mg/L conc
- Key result
- Parameter:
- % degradation (TOC removal)
- Value:
- ca. 81
- Sampling time:
- 28 d
- Remarks on result:
- other: 20 mg/L conc.
- Details on results:
- The two test treatments (10 and 20 mg/L) reached > 60% CO2 production and met the 10 day window ready biodegradation criteria. Reaction products of C16-18/C18 unsaturated fatty acid with methyl diethanolamine, MeCl quaternized can be classified as readily biodegradable.
- Results with reference substance:
- Aniline (20 mg/L) reached >60% CO2 production by day 11. It passed the current test criteria for a reference substance, > 60% CO2 in < 14 days.
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- readily biodegradable
- Conclusions:
- MDEA-Esterquat C16-18 and C18 unsatd. proved to be readily biodegradable (>60% biodegradation after 28 d) in a study conducted in accordance with the OECD TG 301 B, and in compliance with GLP standards.
- Executive summary:
The biodegradation of MDEA-Esterquat C16-18 and C18 unsatd. was studied in accordance with the OECD TG 301 B, and in compliance with GLP standards for 28 d. MDEA-Esterquat C16-18 and C18 unsatd. was applied at 2 concentration of 10 and 20 mg/l. CO2 production was analysed at 0, 1, 4, 5, 7, 8, 11, 14, 18, 22, and 28 days of incubation.The two test treatments (10 and 20 mg/L) reached > 60% CO2 production and met the 10 -day window. Therefore MDEA-Esterquat C16-18 and C18 unsatd. fulfills the OECD criteria of ready biodegradability.
Reference
More details on results
Table: Netto CO2 production and % biodegradation ofreaction products of C16-18/C18
unsaturatedfatty acid with methyl diethanolamine, MeCl
quaternized (MDEA-Esterquat)
Day of test |
10 mg/l |
20 mg/l |
||
mg CO2 cum. netto |
biodegrad. % |
mg CO2 cum. netto |
biodegrad. % |
|
1 |
- 0.42 |
- 0.6 |
0.31 |
0.2 |
4 |
0.0 |
0.0 |
2.29 |
1.7 |
5 |
5.04 |
7.5 |
6.62 |
5.0 |
7 |
15.14 |
22.6 |
29.81 |
22.3 |
8 |
24.55 |
36.7 |
49.19 |
36.8 |
11 |
36.99 |
55.3 |
71.35 |
53.3 |
14 |
40.79 |
61.0 |
82.42 |
61.6 |
18 |
45.19 |
67.6 |
92.27 |
69.0 |
22 |
47.99 |
71.8 |
99.91 |
74.7 |
28 |
50.74 |
75.9 |
106.02 |
79.3 |
Description of key information
The biodegradation of MDEA-Esterquat C16-18 and C18 unsatd. was studied in accordance with the OECD TG 301 B, and in compliance with GLP standards for 28 d. MDEA-Esterquat C16-18 and C18 unsatd. was applied at 2 concentration of 10 and 20 mg/l. CO2 production was analysed at 0, 1, 4, 5, 7, 8, 11, 14, 18, 22, and 28 days of incubation.The two test treatments (10 and 20 mg/L) reached > 60% CO2 production and met the 10 -day window. Therefore MDEA-Esterquat C16-18 and C18 unsatd. fulfills the OECD criteria of ready biodegradability.
Key value for chemical safety assessment
- Biodegradation in water:
- readily biodegradable
- Type of water:
- freshwater
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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