Registration Dossier
Registration Dossier
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EC number: 231-955-3 | CAS number: 7782-42-5
Bioaccumulation: aquatic / sediment
Administrative data
Link to relevant study record(s)
- Endpoint:
- bioaccumulation in aquatic species: fish
- Data waiving:
- study technically not feasible
- Justification for data waiving:
- the study does not need to be conducted because direct and indirect exposure of the aquatic compartment to the substance is unlikely
- other:
Reference
Description of key information
A bioaccumulation study is technically not feasible according to REACH Annex XI, point 2.
Key value for chemical safety assessment
Additional information
OECD test guideline 305 on bioaccumulation in fish is applicable to chemical substances for which it is possible to generate stable solutions in water. Graphite, however, is completely insoluble in water (see IUCLID section 4.8), which is established textbook knowledge. Therefore, stable solutions of the substance in water are impossible to maintain. In view of its insolubility, there is even no bioaccumulation potential of graphite under realistic natural conditions. Neither would a bioaccumulation study employing dietary exposure be feasible or useful since graphite is an inert material that, based on its layered, planar structure forming large macromolecules, can safely be expected to be devoid of any potential to cross biological membranes. In conclusion, due to the physicochemical and structural properties of graphite, performing a bioaccumulation study in fish is technically not feasible, fulfilling the criteria of REACH Annex XI, point 2.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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