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Environmental fate & pathways

Biodegradation in water: screening tests

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Reference
Endpoint:
biodegradation in water: ready biodegradability
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
guideline study without detailed documentation
Qualifier:
according to guideline
Guideline:
OECD Guideline 301 E (Ready biodegradability: Modified OECD Screening Test)
Version / remarks:
September, 1984
GLP compliance:
not specified
Specific details on test material used for the study:
- Name of test material (as cited in study report): Golpanol DP
Oxygen conditions:
aerobic
Inoculum or test system:
sewage, predominantly domestic, non-adapted
Duration of test (contact time):
28 d
Initial conc.:
>= 10 - <= 40 mg/L
Based on:
DOC
Parameter followed for biodegradation estimation:
DOC removal
Details on study design:
The test batches contain inorganic salts dissolved in distilled water and the test substance in a concentration of about 10 to max. 40 mg/L based on their carbon content. At certain intervals, a sample is taken and the dissolved organically bound carbon (= DOC) is determined. The experiment was performed in duplicate.
Reference substance:
not specified
Key result
Parameter:
% degradation (DOC removal)
Value:
73
Sampling time:
28 d
Remarks on result:
other: calculated from 2 experiments
Details on results:
Biodegradation of the test substance was observed: After 7 days, the amount of DOC was decreased by 53% and 41% in replicate 1 and 2, respectively. After 28 days, DOC-content was decreased by 81% and 65% for replicate 1 and 2, respectively. After 28 days, the test substance was degraded for 73% (mean value). See 'Any other information on results incl. tables'.

Measured DOC and inhibition throughout the test

Time

Test substance replicate 1

Decrease (% degradation)

Test substance replicate 2

Decrease (% degradation)

Study initiation

DOC = 21.6 mg/L

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DOC = 21.6 mg/L

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7 Days

DOC = 10.3 mg/L

53%

DOC = 12.8 mg/L

41%

14 Days

DOC = 6.6 mg/L

70%

DOC = 9.9 mg/L

54%

21 Days

DOC = 4.7 mg/L

78%

DOC = 7.7 mg/L

64%

25 days

DOC = 4.7 mg/L

78%

DOC = 7.7 mg/L

64%

28 Days

DOC = 4.2 mg/L

81%

DOC = 7.6 mg/L

65%

Validity criteria fulfilled:
not specified
Interpretation of results:
readily biodegradable, but failing 10-day window

Description of key information

The substance is readily biodegradable but failing 10-day window as observed in a Modified OECD Screening test according to OECD TG 301E.

Key value for chemical safety assessment

Biodegradation in water:
readily biodegradable but failing 10-day window

Additional information

The biodegradation potential of the substance in water was determined in a screening study according to OECD TG 301E (Modified OECD Screening (mod. 301A)) (GLP not specified) (BASF, 1987). In this study, 10 to 40 mg/L test substance (expressed as DOC) was inoculated with non-adapted activated sludge from a predominantly domestic sewage treatment plant for 28 days under aerobic conditions. The DOC-content was determined after 7, 14, 21, 25 and 28 days incubation. The observed decrease in measured DOC-content was expressed as % degradation. After 7 days, the DOC-content was decreased by 53% and 41% in replicate 1 and 2, respectively. After 28 days, the DOC-content had decreased by 81% and 65%, respectively. The mean biodegradation after 28 days was calculated to be 73%. Based on the results, the substance is classified as readily biodegradable. The adaptation phase of the inoculum cannot be accurately determined due to the limited amount of determinations of DOC-content. Consequently, it cannot be determined if the 10-day window criterion was met.