Registration Dossier
Registration Dossier
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EC number: 213-313-4 | CAS number: 936-49-2
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Acute toxicity: via oral route
Link to relevant study records
- Endpoint:
- acute toxicity: oral
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Guideline:
- other: Appraisal of the safety of chemicals in foods, drugs and cosmetics (FDA)
- GLP compliance:
- not specified
- Species:
- rat
- Sex:
- male/female
- Route of administration:
- oral: unspecified
- Vehicle:
- CMC (carboxymethyl cellulose)
- No. of animals per sex per dose:
- 10 animals in total
- Sex:
- male/female
- Dose descriptor:
- LD50
- Effect level:
- 314 mg/kg bw
- Based on:
- test mat.
- Interpretation of results:
- harmful
- Remarks:
- Migrated information Xn;R22 Criteria used for interpretation of results: EU
Reference
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed
- Dose descriptor:
- LD50
- Value:
- 314 mg/kg bw
Acute toxicity: via inhalation route
Endpoint conclusion
- Endpoint conclusion:
- no study available
Acute toxicity: via dermal route
Endpoint conclusion
- Endpoint conclusion:
- no study available
Additional information
Justification for classification or non-classification
With an LD50 (oral, rat) of 314 mg/kg the substance must be classified for acute oral toxicity category 4 with H302 (harmful if swallowed)
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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