Registration Dossier
Registration Dossier
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EC number: 203-472-8 | CAS number: 107-20-0
Endpoint summary
Administrative data
Link to relevant study record(s)
Description of key information
Pertinent data regarding the absorption, distribution or excretion of chloroacetaldehyde could not be located in the available literature. Chloroacetaldehyde is a major metabolite of a number of chlorinated compounds (U.S. EPA, 1980). After oral administration to rats, chloroacetaldehyde is first conjugated with glutathione and subsequently metabolized along two pathways (Green and Hathaway, 1977). Urinary metabolites include N-acetyl(2-hydroxyethyl) cysteine, S-(carboxymethyl) cysteine and thiodiglycollic acid.
Key value for chemical safety assessment
- Bioaccumulation potential:
- no bioaccumulation potential
Additional information
No bioaccumulation is expected due to the high reactivity of chloroacetaldehyde.
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