Hyoscine

Guidance on Safe Use

First-aid measures

General advice :

Remove from exposure, lie down.

Take off immediately all contaminated clothing.

Victim to lie down in the recovery position, cover and keep him warm.

First Aid responders should pay attention to self-protection and use the recommended protective

clothing

Inhalation:

Move to fresh air. Call a physician immediately.

Skin contact:

Wash off immediately with plenty of water. Cover wound with sterile dressing. Call a physician

immediately.

Eye contact :

Rinse immediately with plenty of water for at least 15 minutes.

Keep eye wide open while rinsing.

Call a physician immediately.

Ingestion:

Rinse mouth.

Drink plenty of water.

Call a physician immediately.

Symptoms :

Mouth drynesses,

Dilatation of the pupil,

blurred vision,

Vertigo,

Hallucination,

Disorientation,

rash.

Already μg-doses may cause restlessness, tremor, tachycardia

Risks :

Respiratory paralysis, Coma

Treatment :

Symptomatic treatment (decontamination, vital functions).

Fire-fighting measures

Suitable extinguishing media:

Use extinguishing measures that are appropriate to local circumstances and the surrounding

environment

Water,

Foam,

Dry chemical,

Carbon dioxide (CO2)

Specific hazards during fire-fighting :

In case of fire and/or explosion do not breathe fumes.

Can be released in case of fire:

Carbon oxides,

Nitrogen oxides (NOx)

Specific protective equipment for fire-fighting:

In the event of fire, wear self-contained breathing apparatus.complete suit protecting against chemicals

Further information :

Collect contaminated fire extinguishing water separately.

This must not be discharged into drains.

Fire residues and contaminated fire extinguishing water must be disposed of in accordance with local regulations.

Avoid generating dust; fine dust dispersed in air in sufficient concentrations, and in the presence of an ignition source is a potential dust explosion hazard.

Accidental release measures

Personal precautions :

Wear personal protective equipment

Keep people away from and upwind of spill/leak.

Ensure adequate ventilation.

Knock down dust with water spray jet.

Environmental precautions :

Do not flush into surface water or sanitary sewer system.

Methods for cleaning-up:

Wear personal protective equipment.

Dust deposits should not be allowed to accumulate on surfaces, as these may form an explosive mixture if they are released into the atmosphere in sufficient concentration.

Non-sparking tools should be used.

Avoid dispersal of dust in the air (i.e., clearing dust surfaces with compressed air).

Clean-up methods - large spillage

Dampen, pick up mechanically and dispose of

Clean-up methods - small spillage

Use approved industrial vacuum cleaner for removal.

Keep in suitable, closed containers for disposal.

Handling and storage

Advice on safe handling :

Provide sufficient air exchange and/or exhaust in work rooms.

Routine housekeeping should be instituted to ensure that dusts do not accumulate on surfaces.

Minimize dust generation and accumulation.

Dry powders can build static electricity charges when subjected to the friction of transfer and mixing operations.

Provide adequate precautions, such as electrical grounding and bonding, or inert atmospheres.

Breathing must be protected when large quantities are decanted without local exhaust ventilation.

Keep container closed when not in use.

Advice on protection against fire and explosion:

Keep away from heat and sources of ignition. Take precautionary measures against static discharges.

Avoid dust formation.

Hygiene measures : General industrial hygiene practice. Wash hands and face before breaks and

immediately after handling the product. Keep working clothes separately.

Dust explosion class : Represents a severe dust explosion hazard.

Requirements for storage areas and containers:

Keep tightly closed in a dry and cool place. Keep in a wellventilated place. Protect from heat and direct sunlight. Jointless smooth floor

Advice on common storage :

Keep away from food, drink and animal feedingstuffs. Advice on Segregation

Storage class (TRGS 510) : 6.1AS, Combustible solids, toxic

Specific use(s) : Consult the technical guidelines for the use of this substance/mixture.

Transport information

Land transport (UN RTDG/ADR/RID)

UN number:

1544

Shipping information

Proper shipping name and description:

ALKALOIDS, SOLID, N.O.S.(Scopolamine)

Chemical name:

ALKALOIDS, SOLID, N.O.S.(Scopolamine)

Labels:

6.1

SpecialProvisions

Shipping

Remarks

Marine transport (UN RTDG/IMDG)

UN number:

1544

Shipping information

Proper shipping name and description:

ALKALOIDS, SOLID, N.O.S.(Scopolamine)

Chemical name:

ALKALOIDS, SOLID, N.O.S.(Scopolamine)

Labels:

6.1

Remarks

Air transport (UN RTDG/ICAO/IATA)

UN number:

1544

Shipping information

Proper shipping name and description:

ALKALOIDS, SOLID, N.O.S.(Scopolamine)

Chemical name:

ALKALOIDS, SOLID, N.O.S.(Scopolamine)

Labels:

6.1

Remarks

SpecialProvisions

Exposure controls / personal protection

Engineering measures

It is recommended that all dust control equipment such as local exhaust ventilation and material transport systems involved in handling of this product contain explosion relief vents or an explosion suppression system or an oxygen deficient environment.

Ensure that dust-handling systems (such as exhaust ducts, dust collectors, vessels, and processing equipment) are designed in a manner to prevent the escape of dust into the work area (i.e., there is no leakage from the equipment).

Use only appropriately classified electrical equipment and powered industrial trucks.

Personal protective equipment

Eye protection :

Safety glasses with side-shields

Hand protection

Material : Nitrile rubber

Break through time : 480 min

Glove thickness : 0,43 mm

Directive : Protective gloves against chemicals and micro-organisms

Protective index : Class 6

Skin and body protection : chemical-protection suit

Laboratory: laboratory coat

Respiratory protection : Respirator with a dust filter particle filter P3

Protective measures :

Handle in accordance with good industrial hygiene and safety practice.

Do not breathe dust.

Avoid contact with skin, eyes and clothing.

Only use protective equipment in accordance with national/international regulations. Follow the national regulations about wearing personal protective equipment and the warranty given by the manufacturer for the safe function.

Stability and reactivity

Reactivity:

No dangerous reaction known under conditions of normal use.

Hazardous reactions:

Dust may form explosive mixture in air.

Disposal considerations

Product :

Dispose of in accordance with local regulations.

Contaminated packaging :

Packs that cannot be cleaned should be disposed of in the same manner as the contents.

Uncontaminated packaging can be recycled.