Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: - | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Additional information
Experimental terrestrial data are available for the different trophic levels testing the toxicity of Amines, N-C10-C16-alkyltrimethylenedi-, reaction products with chloroacetic acid on soil invertebrates, plants and microorganisms.
The most sensitive endpoint was determined in soil microorganisms in experiments performed according to OECD 216 and 217. Nitrogen and carbon transformation by soil microorganisms was investigated according to the OECD guidelines 216 and 217. The test item was incorporated into loamy sand soil at nominal concentrations of 1.64, 4.10, 10.24, 25.6, 64, 160, 400, and 1000 mg a.i./kg dry mass at test start. A recalculation revealed that inhibitory effects can be seen at 160 mg a.i./kg dry soil after 28 days. Therefore, the NOEC is 64 mg a.i./kg dry soil.
In a long-term study with invertebrate species Eisenia fetida effects on mortality and biomass were determined after 28 days, the effects on reproduction were determined after 56 days. The test item was applied in concentrations of 313, 625, 1250, 2500 and 5000 mg/per kg dry mass soil, representing 60.9, 122, 244, 488 and 975 mg a.i./kg, respectively. The nominal NOEC for reproduction was found to be the most sensitive assessed endpoint with 1250 mg/kg dry soil, representing 244 mg a.i./kg. No effects were detected in a short-term study with E. fetida according to OECD Guideline 207 and EC method C.8. up to a concentration of 1000 mg a.i./kg.
Two short-term and one long-term study are available testing the toxicity of Amines, N-C10-C16-alkyltrimethylenedi-, reaction products with chloroacetic acid to terrestrial plants.
The key short-term study assessed the effects on the emergence and growth of terrestrial plant seedlings according to OECD guideline 208. Concentration related inhibition of plant growth was observed in Avena sativa (NOEC = 400 mg a.i./kg), Phaseolus aureus (NOEC ≤ 1.64 mg a.i./kg), Raphanus sativus (NOEC = 10.2 mg a.i./kg), Lactuca sativa (NOEC = 160 mg a.i./kg), and Sinapis alba (NOEC = 400 mg a.i./kg). However, for the first three of these five species, the effects were only moderate, with the growth rate never being inhibited by more than 50 %. Accordingly, the EC50 values for these tested species were found to be > 1000 mg a.i./kg dry soil. For Lactuca sativa and Sinapis alba, EC50 values of 363 mg a.i./kg and 400–1000 mg a.i./kg, respectively, were found.
Another short-term toxicity test tested the effects on Amines, N-C10-C16-alkyltrimethylenedi-, reaction products with chloroacetic acid according to the OECD guideline 208. The relevant NOEC for the most sensitive endpoint (growth of Raphanus sativus) was found to be 1515 mg test item per kg dry soil, representing 295 mg a.i./kg. The EC50was calculated to be 4109 mg test item per kg dry soil, representing 801 mg a.i./kg. According to these results, the test item had a mild inhibitory effect on growth in one of the two plant species tested. With respect to seedling emergence and post-emergence survival, no inhibitory effect occurred.
The plant long term-study assessed the effects on the emergence, growth and fertility of terrestrial plant seedlings. The most sensitive NOEC for shoot growth (both, shoot length and fresh weight) of B. rapa and A. sativa at test end were 2500 and 1250 mg test item per kg dry soil, representing 488 and 244 mg a.i./kg, respectively.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.