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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
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EC number: - | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Generally accepted method
- Qualifier:
- no guideline followed
- Principles of method if other than guideline:
- The substance Amines, N-C10-16-alkyltrimethylenedi-, reaction products with chloroacetic acid (20% a.i.), constituting an aqueous solution of the pure active substance, was freeze-dried and the mass of the residue determined gravimetrically
- GLP compliance:
- yes
- Type of method:
- other: no specific method
- Key result
- Water solubility:
- > 208 g/L
- Temp.:
- 20 °C
- pH:
- >= 4 - <= 9
- Conclusions:
- Interpretation of results (migrated information): very soluble (> 10000 mg/L)
The water solubility of Amines, N-C10-16-alkyltrimethylenedi-, reaction products with chloroacetic acid was determined to be > 20.83% (w/w), corresponding to > 208 g/L (pH 4, 7, 9). - Executive summary:
Amines, N-C10-16-alkyltrimethylenedi-, reaction products with chloroacetic acid (20% a.i.), constituting an aqueous solution of the pure active substance, was freeze-dried and the mass of the residue determined gravimetrically.
The water solubility was determined to be > 20.83% (w/w), corresponding to > 208 g/L.
The pH dependence of the water solubility was checked by adjusting three solutions of test substance to pH 4.0, 7.0 and 9.0. At pH 4 and 7 the solution appeared clear. At pH 9 the solution appeared viscous and foamy and appeared clear after several hours. It was concluded the solubility of test substance was not pH dependent over the range tested. Amines, N-C10-16-alkyltrimethylenedi-, reaction products with chloroacetic acid (20% a.i.) remained a clear solution regardless of the pH range tested.
In view of the fact that the active substance as manufactured constitutes an aqueous solution as a “product by process”, the chosen method is considered to be fully justified.
Reference
An aqueous solution of test substance (approximately 20%; colourless to slightly yellow) was weighed, freeze dried and then reweighed. The non-aqueous component of the solution was found to be 20.83% by weight and the solubility was concluded to be >20.83% (w/w). The pH dependence of the water solubility was checked by adjusting three solutions of test substance to pH 4.0, 7.0 and 9.0. At pH 4 and 7 the solution appeared clear. At pH 9 the solution appeared viscous and foamy and appeared clear after several hours. It was concluded the solubility of test substance was not pH dependent over the range tested. Amines, N-C10-16-alkyltrimethylenedi-, reaction products with chloroacetic acid (20% a.i.) remained a clear solution regardless of the pH range tested.
Description of key information
>208 g/L (gravimetrical determination after freeze-drying, non-guideline method; GLP)
Key value for chemical safety assessment
- Water solubility:
- 208 g/L
- at the temperature of:
- 20 °C
Additional information
Amines, N-C10-16-alkyltrimethylenedi-, reaction products with chloroacetic acid (20% a.i.), constituting an aqueous solution of the pure active substance, was freeze-dried and the mass of the residue determined gravimetrically. The water solubility was determined to be > 20.83% (w/w), corresponding to > 208 g/L.
Although the available study was not conducted according to guideline EEC A.6, it is nevertheless established without reasonable doubt that the substance is soluble in water at concentrations of at least 200 g/L. Determination of a more accurate figure would be entirely immaterial for the risk assessment. Thus, the conduct of a water-solubility study following EEC A.6 would not provide a relevant contribution to the existing knowledge and is therefore considered to be scientifically unjustified.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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