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EC number: 214-302-7 | CAS number: 1120-24-7
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
Description of key information
Reliable key studies on ready biodegradability are available for all DMA category members except C16-18u-DMA. These 9 key studies were all performed either according to OECD 301B (CO2-evolution) or OECD 301D (oxygen consumption) guidelines and consistently demonstrated the ready biodegradability of DMAs. For most DMAs, one or more supporting studies are available corroborating the fast and ultimate biodegradability of the category members.
Key value for chemical safety assessment
- Biodegradation in water:
- readily biodegradable
- Type of water:
- freshwater
Additional information
The following table summarizes the available key studies for members of the DMA category (Category member, study type, lab/study number and result):
Available Key studies for DMA category members |
C10-DMA_KEY_301_1996_Huntingdon_96/KAS156/0291: RL2, readily biodegradable (70.2% ThCO2 within 28 d) |
C12-DMA_KEY_301B_1996_Huntingdon_96KAS1620292: RL2, readily biodegradable (72% ThCO2 within 28 d) |
C12-14-DMA_KEY_301F_1992_HOECHST_92-0067-R1/R2: RL2, readily biodegradable (67% ThOD within 28 d) |
C12-16-DMA_KEY_301B_2021_NOACK_AST19237 / SO20651: RL1, readiliy biodegradable (98% ThCO2 within 28 days) |
C12-18-DMA_KEY_301B_2005_Noack_AST97861: RL1, readily biodegradable (93% ThCO2 within 28 d) |
C14-DMA_KEY_301B_2001_Fresenius_IF-100/40587-00: RL1, readiliy biodegradable (71% ThCO2 within 28 d) |
C16-DMA_KEY_301D_1992_AKZO_CRLF91120: RL2, readily biodegradable failing 14-d window (60% ThOD within 28 d) |
C16-18-DMA_KEY_301B_2021_NOACK_AST19238 / SO20652: RL 1, readily biodegradable (100% ThCO2 within 28d) |
C18-DMA_KEY_301D_2005_Akzo_ CER F05044 T 05011 C: readily biodegradable (64% ThOD within 28 d) |
Except for C16-18u-DMA (RA from other category members) for all category members reliable key studies on ready biodegradability (CO2 evolution or O2 consumption) are available, demonstrating >= 60% biodegradation extent within 28 days. For mixtures of homologues of different chain length, the 10- window criterion does not apply. For all mono-constituent DMAs, the 10-day window (or 14-d day window as applicable for the closed bottle test) was met, except for C16-DMA. However, in this case already after 5 days 47% biodegradation was achieved and afterwards the biodegradation curve enters the plateau phase. It is well known that substances which can be metabolized especially well may be fixed to a high degree into bacterial biomass (amplification of bacteria), lowering the measured respiration extent. When the substrate is largely depleted (entry into plateau phase) - in this case between day 5 and day 15 - the remaining slow increase of biodegradation (oxygen consumption) over time may be interpreted as endogenous respiration phase, where the slow increase in biodegradation extent is due to respiration based on a decline of bacterial biomass (bacteria feeding on bacteria). This was convincingly demonstrated by Urano & Kato (1986) by measuring DOC in parallel to BOD to demonstrate substance depletion, plus monitoring of bacterial biomass during MITI (I) tests. The short lag-phase (induction phase) and high slope of the biodegradation curve also corroborates that C16-DMA is readily biodegradable, as does the read-across from the other DMA category members.
In conclusion, the set of reliable key studies conclusively demonstrates the ready biodegradability of all category members of the DMA category. This is further substantiated by several supporting studies, mostly demonstrating the fast and ultimate biodegradability of the category members.
References
Urano, K.; Kato, Z. (1986)
A method to classify biodegradabilities of organic compounds
Journal of Hazardous Materials, 13, 135-145
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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