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EC number: 414-490-2 | CAS number: 154212-59-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 07 Jul - 04 Aug, 1994
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: done under OECD method and GLP
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 994
- Report date:
- 1994
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- EU Method C.4-E (Determination of the "Ready" Biodegradability - Closed Bottle Test)
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 D (Ready Biodegradability: Closed Bottle Test)
- GLP compliance:
- yes
Test material
- Reference substance name:
- -
- EC Number:
- 414-490-2
- EC Name:
- -
- Cas Number:
- 154212-59-6
- Molecular formula:
- C11H9ClN2O5S
- IUPAC Name:
- 4-nitrophenyl (1,3-thiazol-5-yl)methyl carbonate hydrochloride
Constituent 1
Study design
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic (adaptation not specified)
- Details on inoculum:
- The test and std substances were dispersed directly in nutrient medium to give the foloowing series:
a) Inoculated nutrient medium
b) 5mg/l test solution
c) 3mg/l sodium benzoate
d) 5mg/l test solution + 3mg/l sodium benzoate. - Duration of test (contact time):
- 28 d
Parameter followed for biodegradation estimation
- Parameter followed for biodegradation estimation:
- O2 consumption
- Details on study design:
- 280ml BOD bottles were incubated in a water bath at 21±1°C and oxygen detrmination performed at 0, 4, 7, 11, 14, 18, 21, 25 and 28 days.
Reference substance
- Reference substance:
- other: Sodium benzoate
Results and discussion
- Preliminary study:
- A-87439.1 attained 27% degredation after 28 days
- Test performance:
- Sodium benzoate attained 72% biodegredation within 28 days.
% Degradation
- Parameter:
- % degradation (O2 consumption)
- Value:
- 27
- Details on results:
- Nitrate and nitrite analyses were conducted on day 0 and day 28.
Points of degradation plot (test substance):
8 % degradation after 4 d
13 % degradation after 7 d
11 % degradation after 11 d
9 % degradation after 14 d
20 % degradation after 18 d
35 % degradation after 21 d
29 % degradation after 25 d
27 % degradation after 28 d
BOD5 / COD results
- Results with reference substance:
- Points of degradation plot (reference substance):
70 % degradation after 4 d
70 % degradation after 7 d
72 % degradation after 11 d
65 % degradation after 14 d
67 % degradation after 18 d
71 % degradation after 21 d
64 % degradation after 25 d
72 % degradation after 28 d
Any other information on results incl. tables
Oxygen depletion levels in the inoculated control series were within the prescribed limits of ≤1.5mg O2/l after 28 days.
Cultures containing both test and standard substances combined showed an oxygen depletion value 4% lower than that anticipated on the basis of results from separate cultures at day 14. Consequently, A-87439.1 is not considered to have had an inhibitory effect on sewage bacteria under the conditions of the test.
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- other: not readily biodegradble
- Conclusions:
- The test material attained 27% degradation after 28 days and therefore cannot be considered to be readily biodegradable.
- Executive summary:
After correcting the total oxygen consumption (1.355 mgO2/l) for that attributable to nitrification (1.37mg O2/l) the true oxygen consumption value for carbonaceous biodegredation after 28 days is obtained, i.e. 0%.
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