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EC number: 235-120-4
CAS number: 12070-08-5
Titanium carbide was not tested for toxicity to soil micro-organisms and read-across to titanium dioxide (TiO2) was used for this endpoint. Due to lower transformation/dissolution results for titanium carbide (the target substance) than for titanium dioxide (the source substance), the resulting toxicity potential would also be expected to be lower, so read-across is appropriate. Therefore, the dose descriptors are expected to be sufficiently high for the target substances and read-across to the source chemical is adequately protective. A hazard for soil microorganisms is not identified.
the available supporting (yet unreliable) study regarding the
REACH endpoint “toxicity to soil microorganisms”, toxicity o f TiO2
to soil bacteria was determined in the Biolog test over 7
consecutive days. No effects could be observed. The authors report the EC50
(7 d) to be > 100 mg TiO2/L. This result may in
principle be used in a read-across approach to cover the endpoint
requirements for the REACH registration of TiC. Toxic effects to soil
microorganisms arise from exposure via soil pore water. Due to lower
transformation/dissolution results for titanium carbide (the target
substance) than titanium dioxide (the source substance), the resulting
toxicity potential of TiC is also expected to be lower. Therefore, the
dose descriptors are expected to be sufficiently high for the target
substance, and read-across to the source chemical is adequately
fact, (eco-)toxicologically relevant release of Ti ions from titanium
carbide is not expected as the concentration of soluble Ti ions was
below the method detection limit (< 0.4 µg/L) in the T/D test. Thus, TiC
in considered to be practically insoluble. Release of Ti ions to any
ecotoxicologically relevant extent (and potential subsequent formation
of soluble and/or insoluble Ti compounds) is not expected. Therefore,
any toxic effects to soil microorganisms are not expected to arise from
corresponding key study regarding toxicity to soil microorganisms is not
available. However, additional testing is not required as in accordance
with REACH Annex IX, 9.4, column 2, the equilibrium partitioning method
(EPM) based on aquatic data may be applied to assess the hazard to soil
organisms in the absence of reliable toxicity data for soil
microorganisms. However, a hazard for aquatic organisms was not
identified. Consequently, no hazard is identified for soil
microorganisms via the EPM. In addition, the available supporting study
does not indicate toxic effects to soil microorganisms when exposed to
Ti. Besides, experiments with soil macroorganisms and terrestrial plants
do not indicate a hazard for the soil compartment.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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