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EC number: 235-120-4 | CAS number: 12070-08-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data

Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
Titanium carbide was not tested for short-term toxicity to fish, and read-across to titanium dioxide was used for this endpoint.
No deaths were observed at saturation concentration under exposure conditions in acute and prolonged toxicity tests with titanium dioxide; a definitive LC50 could not be determined.
Key value for chemical safety assessment
Additional information
Wahrheit et al. (2007) tested fine TiO2 (380 nm) and ultrafine TiO2 (140 nm) using rainbow trout as test organisms according to the protocol of OECD guideline 203. Fish were exposed for 96 h at nominal test concentrations up to 100 mg TiO2/L (both particle sizes). The LC50 values for fine and ultrafine TiO2 for rainbow trout were determined to be > 100 mg/L.
This result is further supported by Griffitt et al. (2008) who did not observe toxic effects to adult female zebrafish when exposed at nominal concentrations up to 10 mg/L TiO2 for 48 h.
In addition, TiO2 did not exhibit toxic effects in rainbow trout when fish were exposed for 14 days at concentrations up to 1 mg/L (Frederici et al., 2007).
Based on lower transformation/dissolution results for titanium carbide (the target substance) than titanium dioxide (the source substance), the resulting toxicity potential would also be expected to be lower. Therefore, the dose descriptors are expected to be sufficiently high for the target substance, and read-across to the source chemical is adequately protective (for more details refer to the attached description of the read-across approach). In fact, (eco-)toxicologically relevant release of Ti ions from titanium carbide is not expected as the concentration of soluble Ti ions was below the method detection limit (< 0.4 µg/L) in the T/D test. Thus, TiC in considered to be practically insoluble, hence release of Ti ions to any ecotoxicologically relevant extent (and potential subsequent formation of soluble and/or insoluble Ti compounds) is not expected. Therefore, any short-term toxic effects to fish are not expected to arise from TiC.
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