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Partition coefficient

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Description of key information

Using the Rekker calculation method, the partition coefficient log Pow = -3.0 
Using the estimation method from solubilities, the partition coefficient log Pow = -1.3.

Key value for chemical safety assessment

Log Kow (Log Pow):

Additional information

The difference in results using the two methods can be explained by estimations of log Kow values in this low range generally not being very accurate. The calculated log Kow is less than the bioconcentration threshold (log Kow =3) indicating that PDTN is not expected to be susceptible to bioaccumulation.