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EC number: 218-900-9
CAS number: 2277-19-2
The potential of the test substance to cause irritation to eyes was
studied in an OECD Guideline 492 study. The test substance was applied
undiluted to reconstructed human cornea-like epithelium. Negative
controls (distilled water), and positive controls (isopropanol) were
also tested. The test was done in duplicate. The tissues were exposed
for 30 minutes. The mean tissue viability of the test substance was
16.4% of negative controls, which shows potential eye irritant effects.
Since this study alone cannot classify a substance as an eye irritant
according to UN GHS guidelines, further testing will be needed to
determine the eye irritancy potential of the test substance.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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