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EC number: 823-920-1
CAS number: 5341-95-7
Octanol/water partition coefficient test of 2,3-butanediol((2R,3S)-rich)
was performed by the shake flask method following the OECD Test No.107
(Adopted 27.07.95) and in compliance with GLP. Prior to the partition
coefficient test, the validation for the analytical method was
performed, showing recoveries of 2,3-butanediol((2R,3S)-rich) in both
phases (n-octanol and water phase) were 98.8±1.0 and
95.2±3.5%,respectively. The log Powvalues of
2,3-butanediol((2R,3S)-rich)from the all three runs with the different
solvent ratios were -0.82±0.00, -0.84±0.02 and -0.79±0.02, respectively.
Therefore, the average value of log Pow for 2,3-butanediol((2R,3S)-rich)
was determined to be -0.81±0.03. It was within the acceptable range
(less than ±0.3 units) specified by OECD test guideline.
Log Pow for 2,3-butanediol((2R,3S)-rich) was determined to be -0.81±0.03.
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