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EC number: 260-135-8 | CAS number: 56375-79-2
Endpoint summary
Administrative data
Description of key information
Hydrolysis
On the basis of the experimental studies of the structurally and functionally similar read across chemical and applying the weight of evidence approach, the hydrolysis half-life value of the test chemical Tributylmethylammonium chloride can be expected to be ≥ 1 yr at pH 4, 7 and 9 & at a temperature of 20°C or 5 to 63 days, respectively. Thus, based on this half-life value, it can be concluded that the test chemical Tributylmethylammonium chloride undergoes slow to negligible hydrolysis in water.
Additional information
Hydrolysis
Data available for the structurally and functionally similar read across chemicals has been reviewed to determine the half-life of the test chemical Tributylmethylammonium chloride (CAS no. 56375 -79 -2). The studies are as mentioned below:
The half-life of the test chemical was determined at different pH range. The study was performed at pH of 4, 7 and 9, & at a temperature of 20°C, respectively. The half-life period of test chemical was determined to be ≥ 1 yr at pH 4, 7 and 9, respectively & at a temperature of 20°C and thus test chemical was reported to be hydrolytically stable. On the basis of this, test chemical is considered to be not hydrolysable.
In an another study, the half-life of the test chemical was determined.The half-life value of test chemical was determined to be ranges from 5 to 63 days, respectively. Thus, based on the value, test chemical is considered to undergoe slow to negligible hydrolysis in water.
For the test chemical, the hydrolysis half-life value was determined.The hydrolysis of the quaternary nitrogen to a tertiary amine and an alcohol is thermodynamically very unfavorable with a delta G estimated from the delta H of reaction greater than +400 kJ mole. This is predicted to be a very endothermic reaction and should occur only under conditions of very high temperature.Thus, it can be concluded that the test chemical is stable in water and has a hydrolysis half-life of > 1 yr. On the basis of this, test chemical is considered to be not hydrolysable.
On the basis of the experimental studies of the structurally and functionally similar read across chemical and applying the weight of evidence approach, the hydrolysis half-life value of the test chemical Tributylmethylammonium chloride can be expected to be ≥ 1 yr at pH 4, 7 and 9 & at a temperature of 20°C or 5 to 63 days, respectively. Thus, based on this half-life value, it can be concluded that the test chemical Tributylmethylammonium chloride undergoes slow to negligible hydrolysis in water.
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