Registration Dossier
Registration Dossier
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EC number: 241-727-5 | CAS number: 17736-08-2
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
Description of key information
Readily biodegradable: 85.2% in 28 d (OECD 301 B); read-across
Key value for chemical safety assessment
- Biodegradation in water:
- readily biodegradable
Additional information
There is no study available investigating the ready biodegradability of (Z)-N-methyl-N-(1-oxo-9-octadecenyl)glycine, compound with 2,2',2''-nitrilotri(ethanol) (1:1) (CAS 17736-08-2). In accordance with Regulation (EC) No 1907/2006 Annex XI, 1.5 a read-across to the structurally related source substance (Z)-N-methyl-N-(1-oxo-9-octadecenyl)glycine (CAS 110-25-8) was conducted. This read-across is justified in detail within the analogue justification in IUCLID Section 13.
The study with the read-across substance (Z)-N-methyl-N-(1-oxo-9-octadecenyl)glycine (CAS 110-25-8) was conducted according to the OECD guideline 301B using non-adapted activated sludge from a municipal waste water treatment plant. In this CO2 evolution test, 20 mg/L source substance (based on TOC) was inoculated with 25 mg/L activated sludge for 28 d under aerobic conditions and aeration with CO2-free air. Inoculum blanks, an abiotic sterile control and a toxicity control were run in parallel. CO2 was trapped in bottles containing 0.25 M NaOH solution and the evolution of CO2 concentration was followed by TOC analysis in regular intervals. After 28 d incubation, the test item was degraded by 85.2% in terms of CO2 evolution.
Based on the available results from a structurally related read-across substance (in accordance with Regulation (EC) No 1907/2006 Annex XI, 1.5) which is characterized by a similar ecotoxicological profile and comparable structure, it is concluded that (Z)-N-methyl-N-(1-oxo-9-octadecenyl)glycine, compound with 2,2',2''-nitrilotri(ethanol) (1:1) (CAS 17736-08-2) can be expected to be readily biodegradable according to the OECD guideline criteria.
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