Registration Dossier
Registration Dossier
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EC number: 616-077-4 | CAS number: 74332-34-6
Skin irritation / corrosion
Administrative data
- Endpoint:
- skin corrosion: in vitro / ex vivo
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study without detailed documentation
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 011
- Report date:
- 2011
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 435 (In Vitro Membrane Barrier Test Method for Skin Corrosion)
- Version / remarks:
- Corrositex
- GLP compliance:
- not specified
Test material
- Reference substance name:
- (17R)-17-hydroxy-10,13-dimethyl-17-(2-methyl-1,3-dioxolan-2-yl)-1,4,7,8,9,10,12,13,14,15,16,17-dodecahydrospiro[cyclopenta[a]phenanthrene-3,2'-[1,3]dioxolan]-11(2H)-one
- EC Number:
- 616-077-4
- Cas Number:
- 74332-34-6
- Molecular formula:
- C25H36O6
- IUPAC Name:
- (17R)-17-hydroxy-10,13-dimethyl-17-(2-methyl-1,3-dioxolan-2-yl)-1,4,7,8,9,10,12,13,14,15,16,17-dodecahydrospiro[cyclopenta[a]phenanthrene-3,2'-[1,3]dioxolan]-11(2H)-one
Constituent 1
In vitro test system
- Test system:
- artificial membrane barrier model
Results and discussion
In vitro
Results
- Irritation / corrosion parameter:
- other: corrositex
- Remarks on result:
- other: not qualified
Applicant's summary and conclusion
- Interpretation of results:
- study cannot be used for classification
- Conclusions:
- The in vitro corrositivity of cetoxenone was not qualified with Corrositex assay (no further details provided).
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