Registration Dossier
Registration Dossier
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EC number: 201-202-3 | CAS number: 79-39-0
Sensitisation data (human)
Administrative data
- Endpoint:
- sensitisation data (humans)
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Reliability:
- 4 (not assignable)
Data source
Reference
- Reference Type:
- publication
- Title:
- Beitrag zur Wirkung der Alkylmonomere auf die Haut.
- Author:
- Mikulecky Z, Kolisch P, Znojemsky S
- Year:
- 1 960
- Bibliographic source:
- Symposium Dermatologorum Corpus Lectionum 1st: 238-241, Prag 1960, ed. Konopik J.|(Pub. 1962)
Materials and methods
- Study type:
- case report
- GLP compliance:
- not specified
Test material
- Reference substance name:
- Methacrylamide
- EC Number:
- 201-202-3
- EC Name:
- Methacrylamide
- Cas Number:
- 79-39-0
- Molecular formula:
- C4H7NO
- IUPAC Name:
- methacrylamide
Constituent 1
Method
- Route of administration:
- dermal
Results and discussion
- Results of examinations:
- RESULT OF CASE REPORT:
5 patients who were in contact with 1 % methacrylamide (solvent not indicated). They were previously exposed to acrylamide and other acrylates or
methacrylates. 2 out of the 5 patients showed a positive reaction after 72 hours. There were also positive reactions with acrylates. The authors don't distinguish between a irritative- and sensitzing reaction. 30 volunteers (control group) with normal skin reactions showed no positive reactions
when tested with 1 %- or 5 % methacrylamide.
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
