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EC number: 284-366-9
CAS number: 84852-53-9
Poitn mutation and chromosomal aberration tests were negative, both in
the presence and absence of a metabolic activation sytem.
Ames and Chromosome Aberration tests were
negative for the induction of mutagenicity bot in the absence and presence
of a metabolic activation system. An absence of genetic toxicity in mammalian
cells is predicted in a weigh tof evidence approach using literature data
reporting negative QSAR results for EBP and data of a worst case analogous
substance that was clearly negative in a mouse lymphoma assay performed by
Short description of key information:
Guideline- and GLP-compliant Ames and Chromosome Aberration tests
and weight of evidence for genotoxicity in mammalian cells all suggest
that the substance is not genotoxic in the standard in vitro assays.
Endpoint Conclusion: No adverse effect observed (negative)
Non-classification: Ames and Chromosome
Aberration tests were negative for the induction of mutagenicity.
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